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Database: UniProt
Entry: A0A081K674_9GAMM
LinkDB: A0A081K674_9GAMM
Original site: A0A081K674_9GAMM 
ID   A0A081K674_9GAMM        Unreviewed;       539 AA.
AC   A0A081K674;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 24.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=GV64_01845 {ECO:0000313|EMBL:KEI69650.1};
OS   Endozoicomonas elysicola.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Hahellaceae; Endozoicomonas.
OX   NCBI_TaxID=305900 {ECO:0000313|EMBL:KEI69650.1, ECO:0000313|Proteomes:UP000027997};
RN   [1] {ECO:0000313|EMBL:KEI69650.1, ECO:0000313|Proteomes:UP000027997}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22380 {ECO:0000313|EMBL:KEI69650.1,
RC   ECO:0000313|Proteomes:UP000027997};
RA   Neave M.J., Apprill A., Voolstra C.R.;
RT   "Whole Genome Sequences of Three Symbiotic Endozoicomonas Bacteria.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KEI69650.1}.
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DR   EMBL; JOJP01000001; KEI69650.1; -; Genomic_DNA.
DR   RefSeq; WP_034844518.1; NZ_JOJP01000001.1.
DR   EnsemblBacteria; KEI69650; KEI69650; GV64_01845.
DR   Proteomes; UP000027997; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000027997};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027997}.
FT   DOMAIN      236    444       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      447    516       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     244    251       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   539 AA;  60584 MW;  4218C333B50C5FA7 CRC64;
     MPLSLWQKCI DILQDELSSQ QFNTWIRPLK VMGDEHDLCL LAPNRFVADW VKEKFLPRIE
     EILDELSDGE SPAVALAVSN RRPPSLSKRS ARPREVQQAA TVSVSEKPIE NPLKQSGIER
     SVVTHELVSA LPIAQDNTPE PEFVSASTAV NRSSINEELS RTAEDLPQIK VNPLKEQINE
     PSEELVAPAR QVEVEGSIKH HSSLNNGFTF ETFVEGKSNQ LALAAARQVA ENPGASYNPL
     FLYGGVGLGK THLMHAVGNS LVKQNRNARV VYLHSERFVA DMVKALQLNA INDFKKYYRS
     VDALLIDDIQ FFAGKERSQE EFFHTFNALL EGGQQMILTC DRYPKEISGV EERLKSRFGW
     GLTVAVEPPE LETRVAILMK KAEQQKVELP HEAAFFIAQR IRSNVRELEG ALKRVIASAH
     FMGRPIDIDL IRESLKDLLA LQDKQVSIDN IQRTVAEYYK IKVADILSKR RSRSVARPRQ
     VAMALSKELT SHSLPEIGDA YGGRDHTTVL HACRKVKELV EVDNEIKSDY KNLLRSLTS
//
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