ID   A0A081PD54_9SPHI        Unreviewed;       532 AA.
AC   A0A081PD54;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   ORFNames=N180_04315 {ECO:0000313|EMBL:KEQ28627.1};
OS   Pedobacter antarcticus 4BY.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=1358423 {ECO:0000313|EMBL:KEQ28627.1, ECO:0000313|Proteomes:UP000028007};
RN   [1] {ECO:0000313|EMBL:KEQ28627.1, ECO:0000313|Proteomes:UP000028007}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=4BY {ECO:0000313|EMBL:KEQ28627.1,
RC   ECO:0000313|Proteomes:UP000028007};
RA   Shivaji S., Ray M.K., Rao N.S., Saiserr L., Jagannadham M.V., Kumar G.S.,
RA   Reddy G., Bhargava P.M.;
RT   "Sphingobacterium antarcticus sp. nov. a Psychrotrophic Bacterium from the
RT   Soils of Schirmacher Oasis, Antarctica.";
RL   Int. J. Syst. Bacteriol. 42:102-106(1992).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KEQ28627.1}.
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DR   EMBL; JNFF01000110; KEQ28627.1; -; Genomic_DNA.
DR   RefSeq; WP_037443598.1; NZ_JNFF01000110.1.
DR   AlphaFoldDB; A0A081PD54; -.
DR   eggNOG; COG3525; Bacteria.
DR   OrthoDB; 1006965at2; -.
DR   Proteomes; UP000028007; Unassembled WGS sequence.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06563; GH20_chitobiase-like; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028007};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..532
FT                   /note="beta-N-acetylhexosaminidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001761747"
FT   DOMAIN          22..150
FT                   /note="Beta-hexosaminidase bacterial type N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02838"
FT   DOMAIN          153..499
FT                   /note="Glycoside hydrolase family 20 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00728"
FT   ACT_SITE        331
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   532 AA;  60620 MW;  D1F2463A9115BEF0 CRC64;
     MKRYFLSFLL TIYSCCILAQ QPAIIPQPVS IQVQGNMPGF QLQDGTELFA ADSLVRSSAF
     LSAYLKRYHQ LNLKPAAAEQ NDDVSRIILE VGNIPGAFED QYQLQVQPKV IHIRGNSAKA
     VFYGVQTLIQ LFPPVDSAEI SIPAVEIIDY PRFKYRGMHL DVSRHFFDIT FVKQYIDYLA
     LHKLNYFHWH LTDDHGWRIA IDQYPKLTEV GAWRDGTIIG LYPGTGNDGI RYGGFYTKDE
     IKEVIRYAED RYITVVPEIE MPGHAMSILA AYPEFGTNPG TKTRVAQTWG IFNKFNNVLQ
     PTDQTFKFLE NVLGEVIELF PGPYIHIGGD ECAKIWWKQS ALSNRIVQQN GLKDMNGLQS
     YFVNRISKYL ASKGKKMIGW DEILDGGLAP DAIVMSWRGE AGGIAAAKKK HQVIMTPEMK
     TYFNHAQFLK EDSLTAAKLT TLETVYNYDP IPVGLNPADA AYIIGGQGNL WSEYISNPAK
     AEYQLFPRLD ALSEVLWSPK EQRNYTDFQL RLKTQLKRYE LMEINFNKKY LK
//