ID A0A084VYH1_ANOSI Unreviewed; 689 AA.
AC A0A084VYH1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};
GN ORFNames=ZHAS_00010687 {ECO:0000313|EMBL:KFB43015.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB43015.1};
RN [1] {ECO:0000313|EMBL:KFB43015.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC010687-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center {ECO:0000256|RuleBase:RU363050}.
CC -!- SIMILARITY: Belongs to the TUBGCP family.
CC {ECO:0000256|ARBA:ARBA00010337, ECO:0000256|RuleBase:RU363050}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ATLV01018366; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525231; KFB43015.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084VYH1; -.
DR STRING; 74873.A0A084VYH1; -.
DR EnsemblMetazoa; ASIC010687-RA; ASIC010687-PA; ASIC010687.
DR VEuPathDB; VectorBase:ASIC010687; -.
DR VEuPathDB; VectorBase:ASIS004862; -.
DR OMA; QLSMWLL; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR Gene3D; 1.20.120.1900; Gamma-tubulin complex, C-terminal domain; 1.
DR InterPro; IPR007259; GCP.
DR InterPro; IPR040457; GCP_C.
DR InterPro; IPR042241; GCP_C_sf.
DR InterPro; IPR041470; GCP_N.
DR PANTHER; PTHR19302; GAMMA TUBULIN COMPLEX PROTEIN; 1.
DR PANTHER; PTHR19302:SF27; GAMMA-TUBULIN COMPLEX COMPONENT 4; 1.
DR Pfam; PF04130; GCP_C_terminal; 1.
DR Pfam; PF17681; GCP_N_terminal; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU363050};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW ECO:0000256|RuleBase:RU363050};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU363050};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765}.
FT DOMAIN 2..356
FT /note="Gamma tubulin complex component protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17681"
FT DOMAIN 359..681
FT /note="Gamma tubulin complex component C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04130"
SQ SEQUENCE 689 AA; 79047 MW; C154C51D1DF9855F CRC64;
MIHDILFTLF SSNAELPIEN FTIPEVASTF LHPGEIHILE ELLRIANQYK EIKKFIQQYG
TLTAGLLKPK QQKPTEEPLP QGLYLQAFVD GLELVVKPYR DLAVELEAKY LKRPNLSLMF
IFHQVSQYRS LFGFLLQLVS GVVTQRIHGC ALLPYLQQHC LHGNDANYQA VKTIQKSVYV
IFLKQLYGWL MHGKFVDHYG EFFIQQVESN PKGSISTGGG LQQRTQTSVN TFSDSASINS
ELWRYEIRRE MLPYYFPASW AEKVLFVGQT VLMCHFDPRQ HTIDRGTRRA PIAGRKTGGL
SAAAKDSLWG EQEQKLFRKF HQLQNEENLN VTKFEHLVDE IKEQVTMHMS VIVVEEADLV
RQLRLMKDFF LLGRGELFSE FLVQTQSLKL LIGKEITDGT ARDLNRALQL AANSINVGED
IEQFSFELPA NDDDDDEVEE SICYDTKSAI GNIMLKYKVK WPLHLLFSPK ILDRYNEMFR
FLLRIKKIQH DLLQLWSYQR EKRIKHNSDV VQLRNKLMFL INNLQYYLQV DVLESQFAIL
LGVISNTTTK PADFERIQRA HTIFQVNVLS LCFLLASSSS TGEPSSSLGT TTTMAGVIQV
QENPVLTILD SILSIVDRFC SFCMLCKDPM TKMERQEFVT YEQGFMNHVD SLLKLLIGLK
AGPSSAPLSQ LLLRLDFNHW FSSNTQTTA
//
