ID A0A084W7Z1_ANOSI Unreviewed; 623 AA.
AC A0A084W7Z1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=RING-type domain-containing protein {ECO:0000313|EnsemblMetazoa:ASIC014327-PA};
GN ORFNames=ZHAS_00014327 {ECO:0000313|EMBL:KFB46335.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB46335.1};
RN [1] {ECO:0000313|EMBL:KFB46335.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC014327-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ATLV01021323; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525316; KFB46335.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084W7Z1; -.
DR STRING; 74873.A0A084W7Z1; -.
DR EnsemblMetazoa; ASIC014327-RA; ASIC014327-PA; ASIC014327.
DR VEuPathDB; VectorBase:ASIC014327; -.
DR VEuPathDB; VectorBase:ASIS001020; -.
DR OMA; HEAFNQI; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:1904294; P:positive regulation of ERAD pathway; IEA:InterPro.
DR CDD; cd16532; RING-HC_RNFT1-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR044235; RNFT1/2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR15860:SF0; LP20373P; 1.
DR PANTHER; PTHR15860; UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 436..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 511..536
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 564..602
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 282..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..227
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..296
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 302..316
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 66587 MW; 956C171D0D2A2CB5 CRC64;
MSDSNPTADH QRQQTDSQQA GLARTVDPIS PPAETPLPAN STPKEESAAA TIVPTDISIT
VAENTSGSSS ESQSTFPAVD QSLSAEAVPP MPVLPTVQGS SIERQTSVGS IESTTMPSGA
HGGNGTGSSG FRSSFSNGRV SFSRFISVDR TRAANEGNNS SGRGSNFSND IFNDFLSLMQ
QARHPSSLFS SERRGLFLHS GRSHGTGSST PPLSGTNGSI GNTSSSDVVI DVDGSNINAG
ASGTTGVASL RSSHNELYPI STSSSSASTG IRPFLWMQGD DNAASSSNSI GGRSPIAPNF
NYNHHHHHHF HNHQPLHQHL HTSAMAAGGS SAGLSTAGVQ QSPMASGSGI GDSSVPTGNG
EATANGGAST PTGSVPPMAD ATRSNSVSSN HPNDEATVHE AFNQIPEARA MMDTFARYTP
LLLILVAKLC YDHLDGIMHF LLLLMTFYHA NWVVRQEISR QKQRRIIYLM RELIVIGVAL
LIFGLVIEWK SICLVILFMP DHLQPQSLKS LLFSVCITDL ILKLITIIIK IVVTLMPPRV
VDYKSRSYGT VPTKEQLQAC GGQCSICHDN FNSPVLLECN HIFCELCVGT WFDREQTCPL
CRAKIVDDPS YRDGATTFFL QLY
//
