ID A0A085BDM9_9FLAO Unreviewed; 775 AA.
AC A0A085BDM9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=IO90_15655 {ECO:0000313|EMBL:KFC20574.1};
OS Chryseobacterium sp. FH1.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=1233951 {ECO:0000313|EMBL:KFC20574.1, ECO:0000313|Proteomes:UP000028641};
RN [1] {ECO:0000313|EMBL:KFC20574.1, ECO:0000313|Proteomes:UP000028641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FH1 {ECO:0000313|EMBL:KFC20574.1,
RC ECO:0000313|Proteomes:UP000028641};
RA Pipes S.E., Stropko S.J.;
RT "Epilithonimonas sp. FH1 Genome.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFC20574.1}.
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DR EMBL; JPLZ01000006; KFC20574.1; -; Genomic_DNA.
DR RefSeq; WP_034968236.1; NZ_JPLZ01000006.1.
DR AlphaFoldDB; A0A085BDM9; -.
DR STRING; 1233951.IO90_15655; -.
DR eggNOG; COG0210; Bacteria.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000028641; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000028641}.
FT DOMAIN 5..290
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 291..575
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 26..33
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 775 AA; 88302 MW; 26FF4DD681D6D7F7 CRC64;
MDYLKGLNEP QLEAVTTLQG PLMVLAGAGS GKTRVLTMRI AHLIKNGVDP FNILSLTFTN
KAAKEMKERI AKVVGPSDAK SLWMGTFHSV FARILRSEGH HLGYPSNFTI YDMQDALNVM
KKVIKDLNID SDIYKAKKVL SRISQYKNNL ITVNAYFNNP ELMEADEKAN MKLIGEIYKK
YVEACFRNGA MDFDDLLLKT NELLTRFPEV LAKYQDRFRY ILVDEYQDTN HSQYLIVKAL
ASKFENICVV GDDAQSIYSF RGANIYNILN FKKDYPDAVT VSLEQNYRST QNIVDAANVV
ISKNLQQFKK NVFSENEVGE KIKVYRSLSD ADEANFVSAN IFEKHNTQQR HFSDFAILYR
TNSQTRAFED ALRKKNIPYR VYGGLSFYQR KEVKDLLAYL RLLVNENDSE ALARIINFPA
RGIGETTQNK LIVFADSQNV PTTQVLDNLG FYAPQLGLNN GILTKLGDFW AMIKAFQVML
KTDNVYDVAM EVAKRSGLIK LLKEDQTPEG ISRVENIQEL LNSMQGFIEE QIQIEDGDPS
LSNFMENIAL SSDTQNDKDD DTNKVSLMTI HLSKGLEFPV VHLVGLEENL FPSFMSSSTR
EELEEERRLF YVALTRAEKE VFFTYAVSRF QWGKITDAEP SRFLSEIDSK YIELINPLNE
LKFINRSGID SNIFDDTPSE PRFFKKKEEK KTLERNINAP VPKQLKPIAT AKIINPAGQS
SQDIEVGDLV RHDRFGVGEV KFLDGTDPQN IKAKVIFKNE GEKNLILKFA KLTKI
//
