ID A0A085N151_9BILA Unreviewed; 580 AA.
AC A0A085N151;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 13-SEP-2023, entry version 21.
DE RecName: Full=Integrase core domain protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=M514_24672 {ECO:0000313|EMBL:KFD63197.1};
OS Trichuris suis (pig whipworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD63197.1};
RN [1] {ECO:0000313|EMBL:KFD63197.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD63197.1};
RX PubMed=24929829; DOI=10.1038/ng.3012;
RA Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL Nat. Genet. 46:701-706(2014).
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DR EMBL; KL367579; KFD63197.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A085N151; -.
DR Proteomes; UP000030758; Unassembled WGS sequence.
DR GO; GO:0019899; F:enzyme binding; IEA:UniProt.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR025724; GAG-pre-integrase_dom.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR42648:SF11; TRANSPOSON TY4-P GAG-POL POLYPROTEIN; 1.
DR Pfam; PF13976; gag_pre-integrs; 1.
DR Pfam; PF14223; Retrotran_gag_2; 1.
DR Pfam; PF00665; rve; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 220..235
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 481..580
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
SQ SEQUENCE 580 AA; 64606 MW; 6123507C9F3B3BA9 CRC64;
MNTTGGKDSI TLLHGGNYIC WRTKVKAILI GDDLWGIVNV PKPGAPTTAW QKQNNKAMAL
MTLSIEDSQL LHIANCDTGF KMWEKLQKQF ARSSFGSQLY LRRKLYGIRF TSRSMQNHIN
SVLEVVELLK GAGTEITTGE LVAVLLCSLP ESYSGLVTAL EGRDEADLTV EYLTGKVLDE
YQRRTEGSSV GDDSALAMRT SAGQAARMRR HPAAGKKLEC FYCHKMGHFK SECKKRLRDL
RQMNDHGAVA KVMSGDERSG PGSDRKSPQR CTAFTTCERA QIAKANGGWL IDSGCTTLMT
NDRSFFTEMK ETVGEVLLAT KEMTPAKGIG DGRVRCRLPN GNIEDITLRD VLYVPELGGG
LMSVSKITKN GYRVIFENEG CRVKQRSDGA VVVTARLEGN LFLINSVRTV ESVHSAVDTK
ASLEQWHRRF GHRDPNAIKK LLTDGLVHGL ILEGSEHELP PCECCIRGKL NQQPFPNSKS
RAAKPLELIH SDLCGPMQTA TPSGNRYCLT VIDDYSRYAV VRLLKHKSQV PNAIQEIVRE
WTTQVGYKPK VLRTDNGKEY INEWLLRFLK QQGIKHQTTV
//
