ID A0A085NL36_9BILA Unreviewed; 1288 AA.
AC A0A085NL36;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=CKK domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=M514_03269 {ECO:0000313|EMBL:KFD70182.1};
OS Trichuris suis (pig whipworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD70182.1};
RN [1] {ECO:0000313|EMBL:KFD70182.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD70182.1};
RX PubMed=24929829; DOI=10.1038/ng.3012;
RA Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL Nat. Genet. 46:701-706(2014).
CC -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
CC -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
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DR EMBL; KL367489; KFD70182.1; -; Genomic_DNA.
DR Proteomes; UP000030758; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0030507; F:spectrin binding; IEA:InterPro.
DR GO; GO:0031175; P:neuron projection development; IEA:InterPro.
DR Gene3D; 3.10.20.360; CKK domain; 1.
DR InterPro; IPR032940; CAMSAP.
DR InterPro; IPR022613; CAMSAP-like_CH_dom.
DR InterPro; IPR031372; CAMSAP_CC1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR038209; CKK_dom_sf.
DR InterPro; IPR014797; CKK_domain.
DR InterPro; IPR011033; PRC_barrel-like_sf.
DR PANTHER; PTHR21595:SF0; PATRONIN; 1.
DR PANTHER; PTHR21595; UNCHARACTERIZED; 1.
DR Pfam; PF17095; CAMSAP_CC1; 1.
DR Pfam; PF11971; CAMSAP_CH; 1.
DR Pfam; PF08683; CAMSAP_CKK; 1.
DR SMART; SM01051; CAMSAP_CKK; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50346; PRC-barrel domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS51508; CKK; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|PROSITE-
KW ProRule:PRU00841}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 415..544
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1153..1287
FT /note="CKK"
FT /evidence="ECO:0000259|PROSITE:PS51508"
FT REGION 655..676
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..909
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1077..1132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 757..787
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 724..749
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 888..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1084..1132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1288 AA; 143876 MW; 59C488B6FA132C9A CRC64;
MPYNERDANR LAMANMVVRV IGFHFVGSTW IAPVAAVSLA RQGSHCDLSQ SLLLPQWNLY
GNVKSDAVTS DSVEQHQNCK RPDVARHSND RMVSERVHFV SLDVNNRFRT AHTMGCLIGV
VAEEREDKQA TMNGRLVVAK EEETDDSSSL ACWNTKAIDP RQFNNGFLLN VPALLSTLLY
GFAGGSPSSG SRSGSSSAHV HLVATAPGAR SVDEKGARYL QLNAKLRLAF VASAIMDAAV
GQRGFFGKND LLIEPVIDVL PMSEYNAAEA KLRSSVKWLL ARAFGEGLPE EFVDPFYVSG
DNHAQLRPTV VNAMATGELY GLAASSIFHD ELFASDGHKA ILQTLQRYVG QVIDSDGNAV
TETALCQTTP LRVNSHLAMI DHLMAAMTKD VVSGQAVLTA CKKQGPIREN DLPPDNSEGA
LLYWINKVCE CVRDRVETSI ATNGGDAPII PEMDDVYEDI CDGACVATVI SYYHPEKLKF
DDICFNDPMS LTDCIHNLWL IKEFCAKHLP CNVFHFTYED VLYTHETLKP NLNAFLAELF
YFFEGSLADR PVAVPIRRSM GRLETNVTRN QLRKPLKTQI DSTPTRLPNE SKLHSRINSI
DSLMTDRSVD SLKHRHFGTA SGRKLYRSEV DVGNSRPPGT VSFLDISAET NNASLSSFVG
KSPPSYTRSE TMPSVKLHST PSLIRMQLEE KRRLYEAQRQ KRHTELTEQR QKLSKAAFFQ
LKGKEISNSD NSSPTVSQEQ HTTETAKKPS PSAPAEFDEI SKNIKEMQEQ MKRLSMEQEK
LQQLVKSRQE STTLFSPVAA SVAPLFNAQS LICLPSSAFP QMCPSSSVGE MAVQSPVDGN
RQDTAAVDDQ SFMLHANGKR VSRLDPPLEF SNNIASWGMT CSVNRPPRRT WQSLSSSQNG
DQPGGPQYAA SMVDLPACRE AYEEEKAQLA ENFQSASKDA DDNVTCRLEE KTTDGNISMN
GVLEAKPTAT DDGHRRTSAV APFEALADKE RDSSPGIGFV IAAESQKLDE EELLRRKEQK
FARVLRRREE MELRRAKVEE ENAQRRAKLM QRMEEEERRK REKELRRQRV LEEYQKRKAE
QEAMEQSSSS SFGTLPNVTP RSRLTRNQSQ PPVRPKSQMM SSRTALQTDT SSVSNIDRLT
DSCVSEPGLS EPALKLYVKP VQKSNRTIVY NAIQHNVLVG SVNVDVKRKV LEELAKSDGK
HFLLLFRDQK CQFRGLYCWD QTSETVHKLY GVGPKSCTES MMNLLFKYDS GAKQFSYIPS
KHLSATIDAF TIKDDFWQRK QSSLTPRR
//
