ID A0A087EK05_9BIFI Unreviewed; 712 AA.
AC A0A087EK05;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN ORFNames=BITS_0428 {ECO:0000313|EMBL:KFJ08106.1};
OS Bifidobacterium tsurumiense.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=356829 {ECO:0000313|EMBL:KFJ08106.1, ECO:0000313|Proteomes:UP000029080};
RN [1] {ECO:0000313|EMBL:KFJ08106.1, ECO:0000313|Proteomes:UP000029080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 13495 {ECO:0000313|EMBL:KFJ08106.1,
RC ECO:0000313|Proteomes:UP000029080};
RA Ventura M., Milani C., Lugli G.A.;
RT "Genomics of Bifidobacteria.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 42 family.
CC {ECO:0000256|ARBA:ARBA00005940}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFJ08106.1}.
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DR EMBL; JGZU01000003; KFJ08106.1; -; Genomic_DNA.
DR RefSeq; WP_044259212.1; NZ_JGZU01000003.1.
DR AlphaFoldDB; A0A087EK05; -.
DR STRING; 356829.BITS_0428; -.
DR eggNOG; COG1874; Bacteria.
DR OrthoDB; 9800974at2; -.
DR Proteomes; UP000029080; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd03143; A4_beta-galactosidase_middle_domain; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR013738; Beta_galactosidase_Trimer.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR003476; Glyco_hydro_42.
DR InterPro; IPR013529; Glyco_hydro_42_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR36447; BETA-GALACTOSIDASE GANA; 1.
DR PANTHER; PTHR36447:SF2; BETA-GALACTOSIDASE YESZ; 1.
DR Pfam; PF02449; Glyco_hydro_42; 1.
DR Pfam; PF08532; Glyco_hydro_42M; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:KFJ08106.1};
KW Hydrolase {ECO:0000313|EMBL:KFJ08106.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029080}.
FT DOMAIN 15..384
FT /note="Glycoside hydrolase family 42 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02449"
FT DOMAIN 432..620
FT /note="Beta-galactosidase trimerisation"
FT /evidence="ECO:0000259|Pfam:PF08532"
SQ SEQUENCE 712 AA; 79747 MW; 6C63BE54E4DF9C31 CRC64;
MAKTAVDRIL FGAAYYDEYI PRDIDRIDTD MQMMRDAGIN VIRIAESTWS TCEPQPGEFD
FTHIDRALDA ARRYGIQVIV GTPTYAVPAW LVRMHPDVLA QTPAGQGKYG PRQIMDIVNP
AYRYYGERVI RALISHVAYH PSVIGYQIDN ETKYYDSVSP DMQMLFVKHL RKRFHDDLDA
MNAAFGLDYW SNRIDAWEDF PDVSNSINAS LSGAFDAFRR SQVAKFLQWQ GDIVREVARD
DQFITHNFDY DWRGYSFGIQ PAVDHFKAAE AVDIAGVDIY HPSEDGLTGK EIAFGGDVSR
SVKGGRNYIV LETEAQGQHG WLPYPGQLRL QAYSHLASGA DGVMYWHWHS IHNSFETYWR
GLLSHDLEPN PTYREAGVFG REIAQDPLAS QLIHMRKHNA VAIMVSNESL NAMQRFYPYG
AGSGSRLGSG EEQTGYNEVV RRVYDALFDL NVECDFIPTD ASNDTLSRYG MVITPALYCA
SQNTIDALRD YVRQGGHLVS TMRSFVSNED VTVWHDKAPH DLHDVFGMSY NQFTRPQSVA
VEFNGPLDDL DGAEARDIIE LLKPDTDCEV LARYRHYAWG AYAAITRHSF GDGDAEWIAT
DLQEDVLRNV MREAVEHAGV AGVGLALAGV LSVRQGENAQ GRTLTYMLNY SDAEVSAPSP
VSGTVVVAPR IISFDGTVDE EATRNQALQQ GHQVSQGEDL VVPAWNLVVV MS
//
