ID A0A087GUZ2_ARAAL Unreviewed; 542 AA.
AC A0A087GUZ2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=1-phosphatidylinositol 4-kinase {ECO:0000256|ARBA:ARBA00012169};
DE EC=2.7.1.67 {ECO:0000256|ARBA:ARBA00012169};
GN OrderedLocusNames=AALP_Aa5g047700 {ECO:0000313|EMBL:KFK33694.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK33694.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type II PI4K
CC subfamily. {ECO:0000256|ARBA:ARBA00008941}.
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DR EMBL; CM002873; KFK33694.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087GUZ2; -.
DR EnsemblPlants; KFK33694; KFK33694; AALP_AA5G047700.
DR Gramene; KFK33694; KFK33694; AALP_AA5G047700.
DR eggNOG; KOG0001; Eukaryota.
DR eggNOG; KOG2381; Eukaryota.
DR OMA; ICNGFRI; -.
DR OrthoDB; 1699at2759; -.
DR Proteomes; UP000029120; Chromosome 5.
DR GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:UniProtKB-EC.
DR CDD; cd17039; Ubl_ubiquitin_like; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR044571; P4KG1-8.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45800; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA; 1.
DR PANTHER; PTHR45800:SF5; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA 2; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF00240; ubiquitin; 2.
DR SMART; SM00213; UBQ; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000029120}.
FT DOMAIN 29..100
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 105..180
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 226..524
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
SQ SEQUENCE 542 AA; 60084 MW; 50502A6DC4F8EE76 CRC64;
MSVADVAISP IQRGSWFSLS NHYYSVESVL VFLSVSGSTM PMLILESDSI AEVKLRIQTC
NGFRVRRQKL VFSGRELARN ASRVKDYGVT CGSVLHLVLK LCDTLLVTVM ITSCGKVFKF
HVDRSRNVGY LKKRISKEFL DVDDQEILFR GEKLDDNRII DGICKDGNSV IHLLVKKSVP
ALVEDVPPHD SSKDFVLEPV VFNPALKLPK VLEDMIDRTV DGLEKGNAPV RSAEGTGGTY
LMQDSSGLNY VSVFKPMDEE PMAVNNPQKL PLSLDGQGLK RGTRVGEGAT REVAAYLLDH
PKSGPRSLSK EVMGFAGVPP TAMVRSFHKV YNYTKGVSNC TTEDAKVGSL QMFMKNNGSC
EDIGPGAFPV EEVHKISVFD IRMANADRHA GNILTGKGED GKTVLIPIDH GYCLPENFED
CTFEWLYWPQ AKVPFSLDTF DYINSLDSEQ DIALLRLHGW DVPEAVSRTL RISTMLLKKG
VERNLTPYQI GSIMCRETVN KDSAIEEIMR EAHNSVLPAS SEATFLEAVS VAMDHRLDKL
TK
//
