ID A0A087H6Q6_ARAAL Unreviewed; 694 AA.
AC A0A087H6Q6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN OrderedLocusNames=AALP_Aa3g031900 {ECO:0000313|EMBL:KFK37808.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK37808.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
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DR EMBL; CM002871; KFK37808.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087H6Q6; -.
DR EnsemblPlants; KFK37808; KFK37808; AALP_AA3G031900.
DR Gramene; KFK37808; KFK37808; AALP_AA3G031900.
DR OMA; RYETEYI; -.
DR OrthoDB; 920792at2759; -.
DR Proteomes; UP000029120; Chromosome 3.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF600; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE-RELATED; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..169
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 694 AA; 79179 MW; BBD4CD2F8E101940 CRC64;
MASSSSSHDV FTSFRGKDVR RTFLSHLLNE FDRRRIIAFV DNSLTSKSIP PELVRAIRSS
RISIVILSKS YASSSWCLNE LVEIMNCNAS DGQLVMTIFY DVDPSDVRKQ TGDFGKAFKR
TCLGRTEDEK RKWKQALIDV ANILGEHSKN WHSEAAMIKK IATDVSNVLN STPSKDFDNF
VGIEAHIEKM KLELCLENKE AKMIGIWGPA GIGKSTIARA LYDRLSSNFQ LTLFMDNVKA
SYRSNESYSS KLRLQERFLS ELFNDKDLRI KNLGVAEKRL RSRKVLVVLD DVDNIEQLNA
LADRPEWFGN GSRIIVTTED KELLETHEIN LIYEVGFPSR LEALQIFSQS AFRQDSPPDG
YVELANEIAK LTVLPLGLSV LGSSLRGKSK CKWIRALPRL KATLHEDIER ILRVGYDSLG
DNDNLKTIFL YIACLFNGER KDRLTQLLEN SDLDIESGLD VLVERALISI SSDKRIMMHH
LLQQMGQQIV RRQSIHEPGK RQFLLDAKKI NDVLADNTGT GTILGISFNM SEIEELFLGE
NAFIGMHNLQ IIRFYKNRSD KARLHLDEGL DCLRLPLNLR LLHWEACPMK CMPSRFSAKF
LVEINMQESK LEKLWQEDPT LTSLKKINLS TSINLKELPD LSKATNLESV TDIDYKTEGI
GEAIPWEQTI GMQDHQFLRF YRNFMDKGSK LEKL
//
