ID   A0A087QZT4_APTFO        Unreviewed;       717 AA.
AC   A0A087QZT4;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Peroxisomal multifunctional enzyme type 2 {ECO:0000313|EMBL:KFM06738.1};
DE   Flags: Fragment;
GN   ORFNames=AS27_15946 {ECO:0000313|EMBL:KFM06738.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM06738.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM06738.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM06738.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|ARBA:ARBA00005005}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484}.
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DR   EMBL; KL226003; KFM06738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087QZT4; -.
DR   STRING; 9233.A0A087QZT4; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   CDD; cd03448; HDE_HSD; 1.
DR   CDD; cd05353; hydroxyacyl-CoA-like_DH_SDR_c-like; 1.
DR   Gene3D; 1.10.287.4290; -; 1.
DR   Gene3D; 3.10.129.10; Hotdog Thioesterase; 2.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR002539; MaoC-like_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR003033; SCP2_sterol-bd_dom.
DR   InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR45024; DEHYDROGENASES, SHORT CHAIN; 1.
DR   PANTHER; PTHR45024:SF2; SCP2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   Pfam; PF01575; MaoC_dehydratas; 1.
DR   Pfam; PF02036; SCP2; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF55718; SCP-like; 1.
DR   SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286}.
FT   DOMAIN          463..578
FT                   /note="MaoC-like"
FT                   /evidence="ECO:0000259|Pfam:PF01575"
FT   DOMAIN          610..712
FT                   /note="SCP2"
FT                   /evidence="ECO:0000259|Pfam:PF02036"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFM06738.1"
FT   NON_TER         717
FT                   /evidence="ECO:0000313|EMBL:KFM06738.1"
SQ   SEQUENCE   717 AA;  78117 MW;  C3A8D31CC60CBEC0 CRC64;
     GLGRAYALAF AERGASVVVN DLGGDFKGYG KSSSAADKVV NEIRAKGGKA VPNYDSVEDG
     EKLVKTALEA FGRIDIVINN AGILRDRSFV RISDDDWDII HRIHLRGSFL VTRAAWNHMK
     NQKFGRIIMT SSAAGIYGNF GQANYSAAKL GLLGLSNTIA IEGRKYNIHC NTIAPTAGSR
     LTQTVMPQDL VDAFKPEYVA PLVVWLCHES CAENGSLFEV GAGWIGKLRW ERSLGAIVRG
     KNQPMTPEAV RDKWEKVCDF DNASKPRSIQ ESISVLNDAL SQIESQGNVS MNSTSSGSMV
     SSFVDTASIV GRELATNVYE YTHLEPILYA LGVGMSTKDP DHLKFLFEGS EDFCCLPSFG
     VIPAQTSMFD GVPSLPGLNI DLTKMLHGEQ YLELYKPLPT SGQLTSVSTV ADILDKGSGA
     VLLIDVNTYC GKDLVCYNQF SLFFVGAGGF GGKRVSEKAK VTVNPPERPP DAVISDVTTA
     DQAALYRLSG DWNPLHVDPS FAALGGFKKP ILHGLCSFGF AARNVLKQFA NNDVNRFKAI
     KVCVLSRFPG QTLQTEMWKE GNKIHFQTKV KETGEVAIAG GYVDIVPALD KPSAQEPLKT
     AGLQSDLVFE EIGHRVKQIG NELVKKVNAI FQWDITKDGK TAMQWTIDLK NGSGAVYQGP
     ARSSADTIFT LSDEDFMDVV QQKTNPQKAF FSGKLKVKGN IMLSQKLEMI LKDYAKL
//