ID A0A087VFP8_BALRE Unreviewed; 2158 AA.
AC A0A087VFP8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Plexin-B1 {ECO:0000313|EMBL:KFO11440.1};
DE Flags: Fragment;
GN ORFNames=N312_06508 {ECO:0000313|EMBL:KFO11440.1};
OS Balearica regulorum gibbericeps (East African grey crowned-crane).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO11440.1, ECO:0000313|Proteomes:UP000053309};
RN [1] {ECO:0000313|EMBL:KFO11440.1, ECO:0000313|Proteomes:UP000053309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO11440.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- SIMILARITY: Belongs to the plexin family.
CC {ECO:0000256|ARBA:ARBA00010297}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; KL491648; KFO11440.1; -; Genomic_DNA.
DR Proteomes; UP000053309; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR CDD; cd01180; IPT_plexin_repeat1; 1.
DR CDD; cd12793; RasGAP_plexin_B1; 1.
DR CDD; cd11275; Sema_plexin_B1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR041019; TIG1_plexin.
DR InterPro; IPR041362; TIG2_plexin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF36; PLEXIN-B1; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF01833; TIG; 2.
DR Pfam; PF18020; TIG_2; 1.
DR Pfam; PF17960; TIG_plexin; 1.
DR SMART; SM00429; IPT; 3.
DR SMART; SM00423; PSI; 3.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF81296; E set domains; 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053309};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1513..1533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..462
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 686..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 761..780
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..829
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO11440.1"
FT NON_TER 2158
FT /evidence="ECO:0000313|EMBL:KFO11440.1"
SQ SEQUENCE 2158 AA; 240857 MW; 71DB281AF0E85E8C CRC64;
FSRNTTKFLH LSMDLESGTI YLGATNFLFQ LTSDLLMKNM VQTGPVLDSK DCLPPVSKLE
CPQAHHTDNH NKLLLVNTVQ KELIVCGSVH QGICEKRSLT SIDHVLFRPE SPGDTQYVAA
NDPNITTVGL IAYSKDEVPL LFVGRGYTSR GVGGGIPPIT TRNLKAHGGD VQATDSHSIF
SYEETAKLAV GRLSEYNHHF IKSFTYRSSV YFLFYRRDLK SQSREYKTYI SRICLDDSHY
YSYVELPLLC QSKANTYSLL QAAYVTQPGE GLARGQLDTE GEVLFAAFSA WQASSGKLSE
ESALCVYAME EVDRLTNWTR DVCYMRDGKS EEGTEVAYIE YDVSSNCVQL PADTLYAYPC
GSDHTPSPMA SRVPLEAAPL LEKTEARLTA VAVNVEDGHT IAFLGDSRGR LHKVYLGAMG
DAHTYASLAI QLNSMVSGDL LFDQLQEHLF VMTQSMVVKV PILECSLYVD CESCLALKDP
YCGWCVLQGR CSRRSECLRS RLSEQWLWSF NSTQQCLSVQ SLTPANISRE EKRNIFLAIS
DLPSLREEEF YSCYFEDYES PAVLTESGIM CPSPDPSRAP ALPTGADYVT IKLVVRFHDI
FIVSVDFSFY DCAAVALLWK SAPCQKCVSS LWGCNWCVQQ HLCTHKAACE EGTIIYNERV
RLLLGPVPIT ASASCTPLTK SSTTAPAMAT KPVTPPVRVV PSTVPPTELN HVTVSAASDT
KTEPTETLSY TYLTLSTEAA SLQAVTESPL PPPADKPAVT MPDTTSPTAS VLTSPSKNMD
EAALPTEWPT TAQEPRHTNP PTTLPVGSPL HTSTAAVTPS PQVTSFNQVL GGPADDDDSP
GLLGTELPAS ELPPSAPPDW LLEEGMELQD TEDWMDLLQA ENDTSPFSAS TLLSGDGDSS
ERDVSDFPRI LHPDLDYQYD APEFWEDNEE LSWGPDACPC VQGIQGSSLF PVNVARKITL
LGKNFHLYQD QQWDYECVLN LEGRTVVMDA YVEGEETNQS LCYITCQMNQ YSYSAPQLEF
NAVVFVQRRR HLRVDSAADL YVTFYNCSVG HTDCSRCQTA DSKYNCVWCG GDNPSCIFRG
SCKEEVEDLC PAPLIHSVYP LSGPVEGGTR ITITGSNLGQ KHQDIAETVT VAGIPCAVDA
QEYEISSSIV CVTGGSWTER FGHIVVEVPG GGRGVSGHVF TYQNPELKSI VPTQGPKAGG
TCLTLLGSKL LTGHPNEISV LLGDLPCHIL SEMTEDQLTC QTSPSNVSAE LPVTIKYGDQ
ERRLEGSLFR YTLDPNITFA EPPKSFLSGG RVLRVHGYNL DVVQKPKIRV TVSPSERRRR
GLGRWRRIIP DTECPEDALC SVQQFEEPCL VNSSYLILCK TPAINLLLRS VHVKLEFILD
NLSFDFNSLH PMPFSYEVNP ILKPLNAEDP AKPYRHKPGS VISVEGENLD LAISKDEVMA
MIGEGICVVK TLTRNHLYCE PPSEQPAPRH RTKREGTDLL PEFTVQMGNL NFLLGRVQYD
TESQLTFPLE AQIGLGVGAS FVALIVLVIV FIYRRKSKQA LRDYKKVQIQ LENLETSVRD
RCKKEFTDLM TEMMDLTSDL VGTGIPFLDY KSYAERIFFP GHRESPLQRD LDIPECRRQT
VEQGLVQLSN LLNSKLFLTK FIHTLEIQRT FSPRDRAYVA SLLTVSLHGK LEYFTDILKT
LLNDLVEQYV AKNPKLMLRR TETVVEKLLT NWMSICLYAF VRDSVGEPLY MLFRGIKHQV
DKGPVDWVTG KAKYTLNDNR LLREDLEYRT LTLNALTQAG VAAAGAEDSQ GISAKVLDCD
TITQVKEKIL DQIYKGTPYC HRPDPDTLDL EWRSGLAGHL ILSDEDVTSV VQGTWKRLNT
LQHYKVPDGA TVALVPRLTK HIHRENQDYI PGEKTPMLED ADEGGIKLWH LVKPTEEPEL
PKHRRGSLRD RERAKAIPEI YLTRLLSMKG TLQKFVDDLF QVILSTNRPV PLAVKYFFDL
LDEQAMHYGI ADPETIHIWK TNSLPLRFWI NIIKNPQFVF DVQTSDNVDA VLLVIAQTFM
DSCTIADHKL GRDSPINKLL YARDIPRYKQ MVERYYADIR QTISASDQEM NSALAELSRN
YSGDLNSLVA LHELYKYINK YYDQIITALE EDPTAQKMQL GYRLQQIAAA VENKVTDL
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