ID A0A087XRU9_POEFO Unreviewed; 450 AA.
AC A0A087XRU9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Cytochrome P450, family 3, subfamily A, polypeptide 65 {ECO:0000313|Ensembl:ENSPFOP00000008502.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000008502.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000008502.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; AYCK01017428; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01017429; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087XRU9; -.
DR STRING; 48698.ENSPFOP00000008502; -.
DR Ensembl; ENSPFOT00000008514.1; ENSPFOP00000008502.1; ENSPFOG00000008049.1.
DR eggNOG; KOG0158; Eukaryota.
DR GeneTree; ENSGT00950000182958; -.
DR OMA; ARMIFNF; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
DR CDD; cd20650; CYP3A; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR008072; Cyt_P450_E_CYP3A.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24302; CYTOCHROME P450 FAMILY 3; 1.
DR PANTHER; PTHR24302:SF32; CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 65; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
SQ SEQUENCE 450 AA; 52051 MW; DC499411AED9F98C CRC64;
NILNQNNGFF NFDQECYRKY GKIWGIYDGR QPVLCVADPE IIKAILVKEC YSFFTNRRNF
HLNGALYDSL FNAEDDQWKR IRSVLSPSFT SGRLKEMFEI MKSHSANLIH SMKKKADKGE
ALELKEFFGS YSMDVVTSTA FSVDIDSLNN PSDPFVTNIK KMLKFDLLNP LFLARKTFFP
FLGPILEKFE FSFFPKSVTD FFYASLEKIK SNRETSQQKS RVDFLQLMID SQKNNGLQKD
KRLSDHEILS QSMIFIFAGY ETSSSSLTFL AYNLATNPEI MRKLQEEIDS TFPNKAPVQY
QPLMEMDYLD SVINESLRLF PIAARLERVA KASVEINGLV IPKDMVVLVP TWPLHRDPEI
WPEPEKFKPE SRFSKKNKED IDPYTYMPFG VGPRNCIGMR FALVVMKLAV VEILQRYSFS
VCKETEIPFE MDVQGLLAAK RPIQLKLIPR
//
