ID A0A087Y201_POEFO Unreviewed; 355 AA.
AC A0A087Y201;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Transcription factor SOX {ECO:0000256|PIRNR:PIRNR038098};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000012054.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000012054.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR038098}.
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DR EMBL; AYCK01010820; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087Y201; -.
DR STRING; 48698.ENSPFOP00000012054; -.
DR Ensembl; ENSPFOT00000012071.1; ENSPFOP00000012054.1; ENSPFOG00000012067.1.
DR eggNOG; KOG0527; Eukaryota.
DR GeneTree; ENSGT00940000161652; -.
DR OMA; DICQTNW; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR017386; SOX-12/11/4.
DR PANTHER; PTHR10270; SOX TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR10270:SF113; TRANSCRIPTION FACTOR SOX-11; 1.
DR Pfam; PF00505; HMG_box; 1.
DR PIRSF; PIRSF038098; SOX-12/11/4a; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR038098};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Nucleus {ECO:0000256|PIRNR:PIRNR038098, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transcription {ECO:0000256|PIRNR:PIRNR038098};
KW Transcription regulation {ECO:0000256|PIRNR:PIRNR038098}.
FT DOMAIN 46..114
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 46..114
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 355 AA; 39395 MW; B0BBB4746CC105FA CRC64;
MVQHTDHGET DGSMSREATD SEESEFMACS PVAINPDWCK TATGHIKRPM NAFMVWSKIE
RRKIMEQSPD MHNAEISKRL GKRWKMLKDS EKIPFIREAE RLRLKHMADY PDYKYRPKKK
PKLDGSKPSA PSPEKCGKIA KTPSKKCSKI KTKSGSKTAH GYAEDCVFPS IKVAKTVKSE
LTDEDDDDEY EEDYRMGFKA GEEERLRPYG VAKVPASPTL SSSAESEGAS MYEEVRSHNR
LFYNIKSISK QGALHAASVS PASSRSVSGS SSGEDADDLL FDFSLNFAPS AAGSELGNPN
SGNLSLSLVD KDLDSFSEGS LGSHFEFPDY CTPELSEMIA GDWLEANFSD LVFTY
//
