ID A0A087Y8Z0_POEFO Unreviewed; 275 AA.
AC A0A087Y8Z0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=Fas ligand {ECO:0000313|Ensembl:ENSPFOP00000014493.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000014493.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000014493.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the tumor necrosis factor family.
CC {ECO:0000256|ARBA:ARBA00008670}.
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DR EMBL; AYCK01004024; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007550620.1; XM_007550558.2.
DR AlphaFoldDB; A0A087Y8Z0; -.
DR STRING; 48698.ENSPFOP00000014493; -.
DR Ensembl; ENSPFOT00000014515.2; ENSPFOP00000014493.2; ENSPFOG00000014477.2.
DR GeneID; 103137043; -.
DR KEGG; pfor:103137043; -.
DR CTD; 356; -.
DR eggNOG; ENOG502S09I; Eukaryota.
DR GeneTree; ENSGT01060000248544; -.
DR OMA; MACTVNF; -.
DR OrthoDB; 5347330at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0030903; P:notochord development; IEA:Ensembl.
DR CDD; cd00184; TNF; 1.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR006052; TNF_dom.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR11471; TUMOR NECROSIS FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11471:SF33; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 6; 1.
DR Pfam; PF00229; TNF; 1.
DR SMART; SM00207; TNF; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50049; TNF_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..275
FT /note="TNF family profile"
FT /evidence="ECO:0000259|PROSITE:PS50049"
FT REGION 93..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 275 AA; 31271 MW; 36CEB7288B60F39B CRC64;
MSYDQRYPFP QVFLVDEGGG RGESATQPNL IPCWSFPQAR ETVRSRSKSR GCMGVSCSLV
MIVLMLFLLV FAALGFEAWQ ILRLQEKLKN RVEPDPVTES HGPQKQIGLY NPDSNGEEKT
EEKTEEKTKR PAAHVLGRTE YHPSQMTLRW EPKAGQAFTS GSVAYKIEDG ALQVNESGLY
HVYSRVELIF KNCHPTSWFN HVMFVRRVGQ SKPLTLMEAH RSGFCVQKPN SPWTAESYLG
GGLQLMKFDR VYVNVSHPTY LSHSHYGNFF GLYKI
//
