ID A0A087Y9E0_POEFO Unreviewed; 553 AA.
AC A0A087Y9E0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=glucuronosyltransferase {ECO:0000256|ARBA:ARBA00012544};
DE EC=2.4.1.17 {ECO:0000256|ARBA:ARBA00012544};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000014643.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000014643.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004389}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009995, ECO:0000256|RuleBase:RU003718}.
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DR EMBL; AYCK01004977; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007552580.1; XM_007552518.2.
DR AlphaFoldDB; A0A087Y9E0; -.
DR STRING; 48698.ENSPFOP00000014643; -.
DR Ensembl; ENSPFOT00000014665.1; ENSPFOP00000014643.1; ENSPFOG00000014557.1.
DR GeneID; 103138359; -.
DR KEGG; pfor:103138359; -.
DR eggNOG; KOG1192; Eukaryota.
DR GeneTree; ENSGT00940000159677; -.
DR OMA; VALTFKC; -.
DR OrthoDB; 382054at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF157; UDP GLUCURONOSYLTRANSFERASE 1 FAMILY POLYPEPTIDE A3 PRECURSOR-RELATED; 1.
DR Pfam; PF00201; UDPGT; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU003718}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003718};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..553
FT /note="glucuronosyltransferase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001834181"
FT TRANSMEM 520..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 553 AA; 62122 MW; A038146D78D53259 CRC64;
MRKAYFLVLF LLSMAVEGRG AAGKVKDSAE TPKLVKASKV KETATIPEKS GSSSGFLGNL
LVVPMDGSHW VGIKAIAQEM GRRGHRVTVV IPEISIRMGP GKYYDTITYP VPYDRDYMDS
VMTSHKDILE KSSQPFMEKM KKMFSQIQKI TNLLHTTAES LLFNASLISH LAQQNFDAVL
TDPMVPTGLI VAHKLGLPTI NLLRGVPCSL DMKASGCPSP PSFVPRFFTG YTDRMNFKER
VINTLVALLE PLFCRLMFWH FDQIAYDFLE EKVSVAELFA ESAIWLLRID FTLEFPRPLM
PNVILVGGIN CKVRNPLPED LASWLSGEHG FVVFTLGTMV SEMPDYITST FLDAFSQIPQ
KVIWRYTGKF PSRIPDNVKI MKWVPQNDLL AHPGVRAFIT HAGSHGTFEG LCHGVPMVLV
PLAAEQPDNA QKIASRGAGI VLDITSVTTE TLLKGLNEVI NDPRYKENIQ KLSALHNDRP
IDPLDLSVFW TEFVMQHKGA KHLRPAFHDL YWFQYYSLDV MAVLATVLLV FVALTFKCLK
LCLRKLSRKK KQE
//
