ID A0A087YG79_POEFO Unreviewed; 437 AA.
AC A0A087YG79;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=L-fuconate dehydratase {ECO:0000256|ARBA:ARBA00013142};
DE EC=4.2.1.68 {ECO:0000256|ARBA:ARBA00013142};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000017032.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000017032.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O;
CC Xref=Rhea:RHEA:22772, ChEBI:CHEBI:15377, ChEBI:CHEBI:21291,
CC ChEBI:CHEBI:37448; EC=4.2.1.68;
CC Evidence={ECO:0000256|ARBA:ARBA00001737};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; AYCK01006254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007555728.1; XM_007555666.2.
DR AlphaFoldDB; A0A087YG79; -.
DR STRING; 48698.ENSPFOP00000017032; -.
DR Ensembl; ENSPFOT00000017054.2; ENSPFOP00000017032.2; ENSPFOG00000016920.2.
DR GeneID; 103140486; -.
DR KEGG; pfor:103140486; -.
DR CTD; 55556; -.
DR eggNOG; ENOG502QU7C; Eukaryota.
DR GeneTree; ENSGT00390000014290; -.
DR OMA; SGAIDVC; -.
DR OrthoDB; 2903547at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0050023; F:L-fuconate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd03324; rTSbeta_L-fuconate_dehydratase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR034610; L-fuconate_dehydratase.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR InterPro; IPR046945; RHMD-like.
DR PANTHER; PTHR13794; ENOLASE SUPERFAMILY, MANDELATE RACEMASE; 1.
DR PANTHER; PTHR13794:SF58; MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SFLD; SFLDF00111; L-fuconate_dehydratase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 198..294
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 437 AA; 48796 MW; 0E3E9783EA3EC153 CRC64;
MLQKITNLTV RDVRFPTSLE QHGSDAMHTD PDYSAAYVVL DTDSGLKGFG LTFTLGKGTE
IVVRAVQALA GLVVGKSLQD IVSNFRDFYR LLTSDGQMRW LGPEKGVIHL ATAAVLNAVW
DLWARLEGKP LWKLLVDMDP KQVVSCIDFR YITDVLTEEE ALGILVNAKE GKQQREDLMM
SQGYPAYATS CAWLGYSDHQ LKQLCADALQ NGWTRFKVKV GADLKDDIRR CRLIRQMIGP
SNTLMIDANQ RWDVAEAISW VTRLAEVKPL WIEEPTSPDD ILGHAAISKA LAPLGIGVAS
GEQCHNRVMF KQFLQASALQ FVQIDSCRLG SVNENLAVLL MAHKFKVPVC PHAGGVGLCE
LVQHLILFDY ICVSADLSGR MCEYVDHLHE HFTSPVVIQN AHYLTPKDPG YSCEMLESSV
KRHEYPEGDV WKLQLNK
//
