ID A0A089KRA0_9BACL Unreviewed; 315 AA.
AC A0A089KRA0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=R70331_04855 {ECO:0000313|EMBL:AIQ50922.1};
OS Paenibacillus sp. FSL R7-0331.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1536773 {ECO:0000313|EMBL:AIQ50922.1, ECO:0000313|Proteomes:UP000029487};
RN [1] {ECO:0000313|EMBL:AIQ50922.1, ECO:0000313|Proteomes:UP000029487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL R7-0331 {ECO:0000313|EMBL:AIQ50922.1,
RC ECO:0000313|Proteomes:UP000029487};
RA den Bakker H.C., Tsai Y.-C., Martin N., Korlach J., Wiedmann M.;
RT "Comparative genomics of the Paenibacillus odorifer group.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR EMBL; CP009284; AIQ50922.1; -; Genomic_DNA.
DR RefSeq; WP_042173292.1; NZ_CP009284.1.
DR AlphaFoldDB; A0A089KRA0; -.
DR STRING; 1536773.R70331_04855; -.
DR KEGG; paee:R70331_04855; -.
DR eggNOG; COG1793; Bacteria.
DR HOGENOM; CLU_008325_4_0_9; -.
DR Proteomes; UP000029487; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07906; Adenylation_DNA_ligase_LigD_LigC; 1.
DR CDD; cd07971; OBF_DNA_ligase_LigD; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR45674:SF15; DNA LIGASE (ATP); 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AIQ50922.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029487}.
FT DOMAIN 105..223
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 315 AA; 35134 MW; 563E385CB62B149D CRC64;
MEVKPVKPFE PVLAAQLPSG SQWIAQIKWD GVRMLSCYDG SSIELVNRRG NRRTLQYPEL
TVQGRYCRAD SYILDGEVIA LSGGKPSFHE VMRRDGLRSE AAVRAVKPQV PVLYMVFDIL
YCNGEWLLDR PLSVRQQLLQ DVLLPHPHVQ NVPSYTDPAQ LFAAACKGGL EGIICKDIRS
TYAPGGKDAR WQKRKNILDV TAVAGGVTFR DGMVNALLLG LYDDEGRLHY IGHAGAGRLT
ATDWRNLTAQ AHNLEVPVMP FTGVPQRSKD AVWIRPSLVF KLHFLEWNAS GTLRQPVIQA
QVDLPPDACR LEQRG
//
