ID A0A089X5R3_STRGA Unreviewed; 605 AA.
AC A0A089X5R3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SGLAU_12585 {ECO:0000313|EMBL:AIR98513.1};
OS Streptomyces glaucescens.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1907 {ECO:0000313|EMBL:AIR98513.1, ECO:0000313|Proteomes:UP000029482};
RN [1] {ECO:0000313|Proteomes:UP000029482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40922 / GLA O {ECO:0000313|Proteomes:UP000029482};
RX PubMed=25499805; DOI=10.1016/j.jbiotec.2014.11.036;
RA Ortseifen V., Winkler A., Albersmeier A., Wendler S., Puhler A.,
RA Kalinowski J., Ruckert C.;
RT "Complete genome sequence of the actinobacterium Streptomyces glaucescens
RT GLA.O (DSM 40922) consisting of a linear chromosome and one linear
RT plasmid.";
RL J. Biotechnol. 194:81-83(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
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DR EMBL; CP009438; AIR98513.1; -; Genomic_DNA.
DR RefSeq; WP_043501038.1; NZ_CP009438.1.
DR AlphaFoldDB; A0A089X5R3; -.
DR STRING; 1907.SGLAU_12585; -.
DR KEGG; sgu:SGLAU_12585; -.
DR eggNOG; COG1472; Bacteria.
DR HOGENOM; CLU_008392_5_3_11; -.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000029482; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000029482}.
FT DOMAIN 50..390
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 429..605
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
SQ SEQUENCE 605 AA; 63731 MW; 3F3EE23B18E874F1 CRC64;
MPDTSTGNTA KPSRRTVLAA TAGVTAALAV PGPAHAHGDR RLRRLISRMT LEEKVGQLFV
SRAYGHSATA PDQADIDANL REFGVRTPAE LVARYRLGGV IYFAWAHNTR DPHQIAALSN
GLQRASLGLP HRLPLLISTD QEHGIVARIG RPATLFPGAM AIGAGGSRTD ARALGRIAGS
ELRAMGVRQD YTPVADVNVN PANPVIGVRS FGADPDAVAR LVAAETAGYQ RSGVAATAKH
FPGHGDTETD SHYGFPVIRH TRAQWEALDA PPFRAAIEAG IDSIMTAHIL VPALDDSGDP
ATLSRPILTG ILREQLGFDG VVVTDALDMA GVRQKYGDDR VPVLALKAGV DQLLNAPRLD
LAWNAVLKAV QDGELTEERL EESILRVLRL KAKLGLLDDP WTDEDAVDRV VGTAAHLATA
DRIAGRTTTL LVNEGGLLPL APDDTPRLLV VGADPASPSG TTGPPTTVLA RALTELGFTA
TALSTGTAPS AAVIERAVAA AGEADAVVVA TYNVTATSSQ RTLVERLLAT GRPVVAVAVR
NPYDAARLPG VRAYLAAYSW TDVEVRAAAR VIAGQVEPRG KLPVPVQRAD DPTRVLYPLG
HGLTY
//
