ID A0A090AR38_9ENTR Unreviewed; 488 AA.
AC A0A090AR38;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=PTS system glucose-specific EIICB component {ECO:0000256|ARBA:ARBA00021468};
DE EC=2.7.1.199 {ECO:0000256|ARBA:ARBA00011910};
DE AltName: Full=EIICB-Glc {ECO:0000256|ARBA:ARBA00032303};
GN Name=ptsG {ECO:0000313|EMBL:BAP58812.1};
GN ORFNames=TGUWTKB_5870 {ECO:0000313|EMBL:BAP58812.1};
OS Candidatus Tachikawaea gelatinosa.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Tachikawaea.
OX NCBI_TaxID=1410383 {ECO:0000313|EMBL:BAP58812.1, ECO:0000313|Proteomes:UP000031627};
RN [1] {ECO:0000313|Proteomes:UP000031627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UwTKB {ECO:0000313|Proteomes:UP000031627};
RA Kaiwa N., Hosokawa T., Nikoh N., Meng X.Y., Tanahashi M., Moriyama M.,
RA Maeda T., Yamaguchi K., Shigenobu S., Ito M., Fukatsu T.;
RT "Symbiont-containing voluminous jelly as an extraordinary maternal gift for
RT overwintering insect nymphs.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAP58812.1, ECO:0000313|Proteomes:UP000031627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UwTKB {ECO:0000313|EMBL:BAP58812.1,
RC ECO:0000313|Proteomes:UP000031627};
RA Kaiwa N., Hosokawa T., Nikoh N., Tanahashi M., Moriyama M., Meng X.Y.,
RA Maeda T., Yamaguchi K., Shigenobu S., Ito M., Fukatsu T.;
RT "Symbiont-Supplemented Maternal Investment Underpinning Host's Ecological
RT Adaptation.";
RL Curr. Biol. 20:2465-2470(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-glucose(out) + N(pros)-phospho-L-histidyl-[protein] = D-
CC glucose 6-phosphate(in) + L-histidyl-[protein]; Xref=Rhea:RHEA:33367,
CC Rhea:RHEA-COMP:9745, Rhea:RHEA-COMP:9746, ChEBI:CHEBI:4167,
CC ChEBI:CHEBI:29979, ChEBI:CHEBI:61548, ChEBI:CHEBI:64837;
CC EC=2.7.1.199; Evidence={ECO:0000256|ARBA:ARBA00001289};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP014521; BAP58812.1; -; Genomic_DNA.
DR RefSeq; WP_041063386.1; NZ_AP014521.1.
DR AlphaFoldDB; A0A090AR38; -.
DR STRING; 1410383.TGUWTKB_5870; -.
DR KEGG; sbw:TGUWTKB_5870; -.
DR HOGENOM; CLU_012312_1_0_6; -.
DR OrthoDB; 7571469at2; -.
DR Proteomes; UP000031627; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005355; F:glucose transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00212; PTS_IIB_glc; 1.
DR Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR InterPro; IPR036878; Glu_permease_IIB.
DR InterPro; IPR018113; PTrfase_EIIB_Cys.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR InterPro; IPR001996; PTS_IIB_1.
DR InterPro; IPR011299; PTS_IIBC_glc.
DR NCBIfam; TIGR00826; EIIB_glc; 1.
DR NCBIfam; TIGR02002; PTS-II-BC-glcB; 1.
DR PANTHER; PTHR30009; CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT; 1.
DR PANTHER; PTHR30009:SF20; PTS SYSTEM GLUCOSE-SPECIFIC EIICB COMPONENT-RELATED; 1.
DR Pfam; PF00367; PTS_EIIB; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR PROSITE; PS01035; PTS_EIIB_TYPE_1_CYS; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000031627};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..388
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
FT DOMAIN 400..481
FT /note="PTS EIIB type-1"
FT /evidence="ECO:0000259|PROSITE:PS51098"
FT ACT_SITE 422
FT /note="Phosphocysteine intermediate; for EIIB activity"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ SEQUENCE 488 AA; 53019 MW; 8717A52DD071BB3C CRC64;
MFKNVFAGLQ KVGKALMLPV SVLPIAGILL GIGSSKIPWM PHTLSMVMSH AGGAVFENIP
LIFAIGIALG FTNNDGVAAL AAAVSYIIME ETTHLGASLI LGLDLNTSAE KMFVNTGVIG
GILAGAISAY MFNRFYRIKL PDYLGFFSGK RFVPIISGLS VIVIGLLFAC IWPPVGRLVN
RFSQWAAYQN PIMAFGLYGV VERALVPFGL HHIWNVPFQM QIGDFVDNFG RTLHGDIARY
MAGDPTAGKL SGGFLFKMYG LPAAALAIWQ SAKPENKVKI GGIMISAAFT SFLTGITEPI
EFSFLFVEPI LYIIHAILAG LAFPICIILG MRDGFSFSHG FIDFVLLSGN SSKIWLFPIV
GTAYGVIYYT IFRILILSFN LKTPGRELKL ETDDRILQDN EKAEELVTAF GGQNNIVNLD
ACITRLRVTV KDVTKVNQDK LKSLGAQSVL VVGSGIQAIF GTNSDNLKTS MDEYMQSIKE
KNNALKSS
//
