ID A0A090KDF4_9GAMM Unreviewed; 377 AA.
AC A0A090KDF4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN Name=hphIBM {ECO:0000313|EMBL:CED61893.1};
GN ORFNames=MVIS_4012 {ECO:0000313|EMBL:CED61893.1};
OS Moritella viscosa.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Moritellaceae; Moritella.
OX NCBI_TaxID=80854 {ECO:0000313|EMBL:CED61893.1, ECO:0000313|Proteomes:UP000032438};
RN [1] {ECO:0000313|Proteomes:UP000032438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hjerde E.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
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DR EMBL; LN554852; CED61893.1; -; Genomic_DNA.
DR RefSeq; WP_045111957.1; NZ_FRDW01000096.1.
DR AlphaFoldDB; A0A090KDF4; -.
DR STRING; 80854.MVIS_4012; -.
DR GeneID; 61298015; -.
DR KEGG; mvs:MVIS_4012; -.
DR PATRIC; fig|80854.5.peg.4256; -.
DR HOGENOM; CLU_058001_0_0_6; -.
DR Proteomes; UP000032438; Chromosome complete sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.1020.10; Adenine-specific Methyltransferase, Domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR023095; Ade_MeTrfase_dom_2.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR012327; MeTrfase_D12.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF02086; MethyltransfD12; 1.
DR PRINTS; PR00505; D12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CED61893.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000032438};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CED61893.1}.
SQ SEQUENCE 377 AA; 43212 MW; CEC320B2480BBEB0 CRC64;
MLENQQLTID CNIDNSGVNR MKVKALDLPK FPTTRYQGSK RKILPELATA LSTVNYTKAL
DMFSGSGVVS LLFRTLDKDI SSNDFMLYNQ NTAKVFQQFN LDNLNNLEIK KDLEDLLYKL
PVNEEKLVSK HFHNIYFIDS ENIEIDRFCQ NINTYNDFAK SVYIYAIGQA LTKKRPYNLF
HRANLEMRTK EVERSFGNKK TWDTSMFDHA IKCINELKKF PINEVKELNK NVTGFNSSEL
DSFSNDFDLI YLDPPYINGK GTSVDYSNFY HFLEGLCDYQ LFGSANDKYP HKPIVKKPSA
WLKPDTALIE LTAICERWPN ATIVFSYRSD GLPIPVEAAK AMSTNGRVAE IHSAGEYKYA
LSKTNTNEEL IIIARPA
//
