ID A0A090LEA1_STRRB Unreviewed; 601 AA.
AC A0A090LEA1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Proteinase inhibitor I2, Kunitz metazoa domain and Cysteine-rich repeat and Lustrin, cysteine-rich repeated domain-containing protein {ECO:0000313|EMBL:CEF66473.1};
GN ORFNames=SRAE_2000114100 {ECO:0000313|EMBL:CEF66473.1,
GN ECO:0000313|WBParaSite:SRAE_2000114100.1,
GN ECO:0000313|WormBase:SRAE_2000114100};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF66473.1};
RN [1] {ECO:0000313|EMBL:CEF66473.1, ECO:0000313|Proteomes:UP000035682}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_2000114100.1}, and ED321 Heterogonic
RC {ECO:0000313|EMBL:CEF66473.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SRAE_2000114100.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
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DR EMBL; LN609529; CEF66473.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A090LEA1; -.
DR STRING; 34506.A0A090LEA1; -.
DR EnsemblMetazoa; SRAE_2000114100.1; SRAE_2000114100.1; WBGene00261343.
DR WBParaSite; SRAE_2000114100.1; SRAE_2000114100.1; WBGene00261343.
DR WormBase; SRAE_2000114100; SRP01269; WBGene00261343; -.
DR OMA; CCQKADR; -.
DR OrthoDB; 2871984at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00109; Kunitz-type; 1.
DR CDD; cd22593; Kunitz_conkunitzin; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 2.
DR InterPro; IPR006150; Cys_repeat_1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR028150; Lustrin_cystein.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR PANTHER; PTHR46339:SF10; PROTEIN CBG13502; 1.
DR PANTHER; PTHR46339; PROTEIN CBG15282-RELATED; 1.
DR Pfam; PF00014; Kunitz_BPTI; 2.
DR Pfam; PF14625; Lustrin_cystein; 6.
DR SMART; SM00131; KU; 2.
DR SMART; SM00289; WR1; 8.
DR SUPFAM; SSF57362; BPTI-like; 3.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 2.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..601
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015030729"
FT DOMAIN 24..77
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 129..181
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
SQ SEQUENCE 601 AA; 67225 MW; 6F2A293C6761DE7D CRC64;
MYCIILFSSF LIVSKSVELG GVLCSQPKNY GYECGKFKPH IAYYFDINIL KCVKFQFKGC
GGNQNRFGTY NECNNGCGSL STCRKGLPYM DFGGNIKHCN NGKIKCPYGY ECVGIGSQSV
CCKEKETICA MNVEPGKGCN ILPETRYFFD SSANVCRSFI YLGCGGNDNN FHSKGDCMKY
CQKEISCLKG EPYPDRFSPS RSLHCKTNKD CPTNYECYGK NNENKACCRT LESVCTTKYI
SDVACVAKHD IKKIWTFDYK MGYCIEKNEI SCLDQINSFA NLEQCTDYCI GTCPNGMQIH
INWITNQPQL CNYEKQLGCP IGYECIKTSN ITAICCKTPP TCMLEGSLSY SLPTTNEPIR
CNPKSQQSCP FNYQCQEAKN KEYICCTPKI ECPYGMEILK YSKNEIKICT PDIPGTCPNN
DNYLCIKGQN TNVNVCCKVK KTCISPYVNI QTKKPKKCFP GESICPEGTH CLQNKDLSLI
ESNKNNTINI SSKIFHCCYD MNIYSCPNND EPILNTTTGL PYECNPSIGK SCPYQYECKE
LLDSSYACCP LPKNELCKEA VLNPSTGNPV SCKGPDDKLS CLMTSSTCKL TSNNGYYCCK
K
//
