ID A0A090LJ07_STRRB Unreviewed; 862 AA.
AC A0A090LJ07;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=SRAE_2000216700 {ECO:0000313|EMBL:CEF67505.1,
GN ECO:0000313|WBParaSite:SRAE_2000216700.1,
GN ECO:0000313|WormBase:SRAE_2000216700};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF67505.1};
RN [1] {ECO:0000313|EMBL:CEF67505.1, ECO:0000313|Proteomes:UP000035682}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_2000216700.1}, and ED321 Heterogonic
RC {ECO:0000313|EMBL:CEF67505.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SRAE_2000216700.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
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DR EMBL; LN609529; CEF67505.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A090LJ07; -.
DR STRING; 34506.A0A090LJ07; -.
DR EnsemblMetazoa; SRAE_2000216700.1; SRAE_2000216700.1; WBGene00262376.
DR WBParaSite; SRAE_2000216700.1; SRAE_2000216700.1; WBGene00262376.
DR WormBase; SRAE_2000216700; SRP09360; WBGene00262376; -.
DR eggNOG; KOG0335; Eukaryota.
DR OMA; ANKCITQ; -.
DR OrthoDB; 2881785at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0043186; C:P granule; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000035682}.
FT DOMAIN 474..502
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 505..684
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 723..862
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 29..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 474..502
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 29..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..93
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..393
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 862 AA; 93345 MW; A2CB191C8134E022 CRC64;
MSRRGLSSGV SNSAFANFHS FRSALPSKVE VSNTNDENIK PQSTNLYDSQ QGSAQYQNSS
PCGDNDDGEK NDFNCTSAKD DYPDTSTSDA FGRVNEGSFN YSCNESSSQV NSDNPDRSGK
EVFGLHNNEE SSRHVNFGGS GRGGSVTFGS NYNEKSSESV NFASSGRGRR GISGGYDNAD
SSGHVNFGNS GRGGRGAFGS NYNEDSSGNV NFGSSGRGGR GAFGSNYNED SSGNVNFGAS
GRGGRGAFRS HDNGDSSGHV NFGNSGRGGR GAFGSNYNED SSGHVNFGSS GRGGRGAFGS
NYNEDSSGHV NFGSSGRGGR GTFGSNYNED LSGHVNFGNS GRGGRGAFRS HDNGDSSGHV
NLGSSGRGRR GISEAYDNGH SSGHVNFGSS GRGGRGGSNY FSTKSNNYGG GDINEFLGNA
HSGQKLLAAT HVPIDRSIEI LLDEDKRNNI FYSQVADQDD DVDVSGASYR FKFESWAECE
FVPELMENIK LTGYVKPRNI QAFTMPQIMN GFDVKGQAET GSGKTAAFLL PIINDIIANN
YERKPQSPIA IIISPTRELA LQTHEQARKF AHKTGVTAAK CYGQYKVSEN IVEIRNGCDI
LSATPGRLKS FVLNGDISLQ CLRFFILDEA DELFTYDFVQ TIRECLSIGN APPKDKRINM
LFSATFPSGV DELASELLNE NYVTIVNSSQ NGANKKVSHE ILCVDKRQKN IKVCDMLLKE
KKDVEQTGQL LRRTLIFVSR KQQADMLAMF FCERGIDALS LNGDRPQKLR EEALNDFRAH
KISVLVTTDV CARGIDIKDL DHVINVDLPK EFVTFVHRVG RTGRLREGFA TSFYDPSDDY
NLKEDLVNLL RLNAKDVPEF LL
//
