ID A0A090LKW0_STRRB Unreviewed; 439 AA.
AC A0A090LKW0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=DnaJ homolog subfamily A member 2 {ECO:0000313|EMBL:CEF68798.1, ECO:0000313|WBParaSite:SRAE_2000345300.1};
GN ORFNames=SRAE_2000345300 {ECO:0000313|EMBL:CEF68798.1,
GN ECO:0000313|WBParaSite:SRAE_2000345300.1,
GN ECO:0000313|WormBase:SRAE_2000345300};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF68798.1};
RN [1] {ECO:0000313|EMBL:CEF68798.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 Heterogonic {ECO:0000313|EMBL:CEF68798.1};
RA Aslett A.Martin.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000035682, ECO:0000313|WBParaSite:SRAE_2000345300.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_2000345300.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:SRAE_2000345300.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-
CC anchor {ECO:0000256|ARBA:ARBA00004635}.
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DR EMBL; LN609529; CEF68798.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A090LKW0; -.
DR STRING; 34506.A0A090LKW0; -.
DR EnsemblMetazoa; SRAE_2000345300.1; SRAE_2000345300.1; WBGene00263675.
DR WBParaSite; SRAE_2000345300.1; SRAE_2000345300.1; WBGene00263675.
DR WormBase; SRAE_2000345300; SRP03450; WBGene00263675; -.
DR eggNOG; KOG0712; Eukaryota.
DR OMA; RVCPTCV; -.
DR OrthoDB; 2785358at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0030544; F:Hsp70 protein binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR GO; GO:0009408; P:response to heat; IEA:InterPro.
DR CDD; cd06257; DnaJ; 1.
DR CDD; cd10747; DnaJ_C; 1.
DR CDD; cd10719; DnaJ_zf; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 2.10.230.10; Heat shock protein DnaJ, cysteine-rich domain; 1.
DR Gene3D; 2.60.260.20; Urease metallochaperone UreE, N-terminal domain; 2.
DR HAMAP; MF_01152; DnaJ; 1.
DR InterPro; IPR012724; DnaJ.
DR InterPro; IPR002939; DnaJ_C.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR044713; DNJA1/2-like.
DR InterPro; IPR008971; HSP40/DnaJ_pept-bd.
DR InterPro; IPR001305; HSP_DnaJ_Cys-rich_dom.
DR InterPro; IPR036410; HSP_DnaJ_Cys-rich_dom_sf.
DR InterPro; IPR036869; J_dom_sf.
DR PANTHER; PTHR43888:SF31; DNAJ HOMOLOG SUBFAMILY A MEMBER 2; 1.
DR PANTHER; PTHR43888; DNAJ-LIKE-2, ISOFORM A-RELATED; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF01556; DnaJ_C; 1.
DR Pfam; PF00684; DnaJ_CXXCXGXG; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF57938; DnaJ/Hsp40 cysteine-rich domain; 1.
DR SUPFAM; SSF49493; HSP40/DnaJ peptide-binding domain; 2.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS51188; ZF_CR; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00546}; Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00546};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00546}.
FT DOMAIN 25..87
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT DOMAIN 147..232
FT /note="CR-type"
FT /evidence="ECO:0000259|PROSITE:PS51188"
FT ZN_FING 147..232
FT /note="CR-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00546"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 439 AA; 48582 MW; EAB11143BCD80574 CRC64;
MGGGFPSGGS FYHGGHGSSS PADTKLYDIL GVKPDASDSE IKKAYRRLAR EYHPDKNSDH
GDKFKEISAA YEILSDENKR KIYDQQGMEG LRGGGGDGGP GFDIFDMFGE STFGSFFGGG
RSGPPKKKRG RDTLHKLRIS LVDAYKGKLS KLKLSRKVIC QSCKGFGGAN GVKPQTCTKC
HGRGVYMMTR RVGPGMITSQ QVRCDECRGE REVLAEKDKC RSCSGEKIVD ETKILTVDIM
PGVKQNQEFV FKGEGDQYPG VETGNVKIIV EIEKHPEFER QGRDLVYNKT LTLTEALCGF
AFTIKQLDGR ILLVENRPGN VIEPDSVRCV YGEGMPWVEN RTQKGNLYIK FDIKFPTSYF
LKNEEDYKKL EKCLPPRPKP EGMNFSAAEH VTLNECEGVN LNGGGGGGRR GEAYQEDYDD
EDMDNESGHG HGGVECRQQ
//
