ID   A0A090LXU8_OSTTA        Unreviewed;      1417 AA.
AC   A0A090LXU8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   SubName: Full=Clathrin, heavy chain/VPS, 7-fold repeat {ECO:0000313|EMBL:CEF96631.1};
GN   ORFNames=OT_ostta01g02350 {ECO:0000313|EMBL:CEF96631.1};
OS   Ostreococcus tauri.
OC   Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC   Bathycoccaceae; Ostreococcus.
OX   NCBI_TaxID=70448 {ECO:0000313|EMBL:CEF96631.1, ECO:0000313|Proteomes:UP000009170};
RN   [1] {ECO:0000313|Proteomes:UP000009170}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OTTH0595 {ECO:0000313|Proteomes:UP000009170};
RX   PubMed=16868079; DOI=10.1073/pnas.0604795103;
RA   Derelle E., Ferraz C., Rombauts S., Rouze P., Worden A.Z., Robbens S.,
RA   Partensky F., Degroeve S., Echeynie S., Cooke R., Saeys Y., Wuyts J.,
RA   Jabbari K., Bowler C., Panaud O., Piegu B., Ball S.G., Ral J.-P.,
RA   Bouget F.-Y., Piganeau G., De Baets B., Picard A., Delseny M., Demaille J.,
RA   Van de Peer Y., Moreau H.;
RT   "Genome analysis of the smallest free-living eukaryote Ostreococcus tauri
RT   unveils many unique features.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:11647-11652(2006).
CC   -!- SIMILARITY: Belongs to the VPS8 family.
CC       {ECO:0000256|ARBA:ARBA00009422}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CEF96631.1}.
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DR   EMBL; CAID01000001; CEF96631.1; -; Genomic_DNA.
DR   STRING; 70448.A0A090LXU8; -.
DR   InParanoid; A0A090LXU8; -.
DR   OrthoDB; 120292at2759; -.
DR   Proteomes; UP000009170; Chromosome 1.
DR   GO; GO:0006623; P:protein targeting to vacuole; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR045111; Vps41/Vps8.
DR   InterPro; IPR025941; Vps8_central_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12616; VACUOLAR PROTEIN SORTING VPS41; 1.
DR   PANTHER; PTHR12616:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG; 1.
DR   Pfam; PF12816; Vps8; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009170};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          241..275
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          694..856
FT                   /note="Vacuolar protein sorting-associated protein 8
FT                   central"
FT                   /evidence="ECO:0000259|Pfam:PF12816"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          82..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..100
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1417 AA;  154644 MW;  3F217ADC400C72AF CRC64;
     MGARRWAPVG GEDDGLTSSD DDETCDSVRV DDLLVSSSSD AEDDGANAEG EIPSVRAVER
     LEVGEETMVK DEDVRAAVRR AARRRARGDA RERDSSDAEG EGEGSESEDG LVVALAREAR
     AFEGIHGARS TSATDAREEA RRALETLRLR ARSGKRRSAG NAKGSVGCVV DLSNVRRVTD
     AMMDTVDAGR AMCCASGAGG RVAVGTEGGF IFLERGASGE TTMSILRSAN NFAGISATPG
     VTSLCFDERG DWLLAGHDDG GLTLWDVKRN PTILKTVVGV HRTPIVALVM LAKANSSGAV
     DVVSSEEGGL VIHHTFSPLG MGVIRVKSSS LGERTFVIAA QALPSAATVD VNDLKEHENG
     VVSSYFGETS SATKGVADSA GIVALNTMNA VLVMRLNPKA EVIAKIVRPP NMASSVLPIM
     HWSPRWAEDI IMREGVEVCN LIVVWGASVY VLAVDVESVK PAPDKGEERS KRASNTSRII
     HSWKMDSEAS TTALAAAWLA QDLICILSSR NKLLIYTPSG ELVERIPTGE PPVPREFVRG
     VTGNDAGSER VQNWHGSVTM HGVYIAILSP SRLRQGKFLG WLERVRAKKL DEDWIGAFDT
     LLQAYAEELP LWPALSKKYA DVETTRMRVV EAFISEIPSF LDAYSRVDEN EEPEYLANLT
     RAIFALLLVF DALDKVYAPA VFDAFLNSKC RANFLEGMVP HILTDKLRSL PAEVMQALVE
     HYASLGEADT IEKCVLHMDV TSLDLNQIAR LCKHHGMFSA LAHVFTRALN DFVTPIEAMF
     QASLVPAFGD KVRVRQLLLF IHKTIRGERF PIVGDELSSD VVARFRFEVM KFLLEPVDVS
     TFTSSESTKE SIAVNTWMTA MQLIERESAS TQPPPLRLLY LFLIEPKATT DVMAEFLKNW
     DASEIEIMGV DRQECDRMAS QIVAEVAVLT ANAFGSGGHT SSRSQLLTFT ASLVGSGRAA
     VSQEIERELL EELALTSTKR DAQKREDAMV LIISRRIEED IVLSDESRML ELARGAHFAQ
     AEAVIHISSG DHISALKTLA GDAHRPNAAV HYVDVLLGTA TAGKVMAEQV NAGPAVARAH
     ALDAEMAKSF YEEILAIMPA LAGTSADVCA RIAIAHFPLA QDEVLRALSS EPVLQFQYLR
     QVLETVHGGG VMSEGQNMSL AELVSSTKSI VTAEMSELYL RLMCQFEPQD VLKYLQSESG
     KSLDQAQCLE HCREFNVMDA LAYLLEALGK HDEALSIHLS SYSTGVRAMI QLSTTGGAEW
     ARTAPAESLM KGLIIEASES LRVAIALCRR VSSGVQNGEE MWWSCLDSIV RSLLALGDGD
     YVRVRDMLDE QLDEVLRVML GRVDNGHLLE MIVARYGNED ISELRKLLSR VFGNCASERD
     FLKAEGTVVQ EEADRKVLKN ETIRRRAQRG TRRTVTY
//