ID A0A090QKY5_9FLAO Unreviewed; 1046 AA.
AC A0A090QKY5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=JCM19294_2968 {ECO:0000313|EMBL:GAK96186.1};
OS Nonlabens tegetincola.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Nonlabens.
OX NCBI_TaxID=323273 {ECO:0000313|EMBL:GAK96186.1, ECO:0000313|Proteomes:UP000029221};
RN [1] {ECO:0000313|EMBL:GAK96186.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 19294 {ECO:0000313|EMBL:GAK96186.1};
RA Nakanishi M., Meirelles P., Suzuki R., Takatani N., Mino S., Suda W.,
RA Oshima K., Hattori M., Ohkuma M., Hosokawa M., Miyashita K., Thompson F.L.,
RA Niwa A., Sawabe T., Sawabe T.;
RT "Draft Genome Sequences of Marine Flavobacterium Nonlabens Strains NR17,
RT NR24, NR27, NR32, NR33, and Ara13.";
RL Genome Announc. 2:e01165-14(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAK96186.1}.
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DR EMBL; BBML01000001; GAK96186.1; -; Genomic_DNA.
DR RefSeq; WP_042277205.1; NZ_BBML01000001.1.
DR AlphaFoldDB; A0A090QKY5; -.
DR STRING; 319236.BST91_10065; -.
DR eggNOG; COG1074; Bacteria.
DR Proteomes; UP000029221; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 1.10.3170.10; Recbcd, chain B, domain 2; 1.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF64; ATP-DEPENDENT DNA HELICASE REP; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000029221}.
FT DOMAIN 1..467
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 479..737
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 11..18
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1046 AA; 121217 MW; F488DC26F657F062 CRC64;
MTHQPTTIYS ASAGSGKTYT LARDFLTKLL SQKTNRGYRY ILAVTFTNKA VAEMKTRILE
YLKELGQAEW SDKIVPIAQH VQSQSGLSEQ QLKDKSHRVL QYLLHDYAAF DVVTIDTFNH
RLLRTFSKDM KLPDGFQVAL DTDELIEKAV NQVIDRAGND KQLTDILVEY ALEKIDNDRS
WNIAIDLQKM AKRIGSENNY RYLKDLKNKD ISEFVRFRES VKKKIHSLRQ SITDGAIEID
SQRLKMGWTI NDFSYKSTGA IGQIQKLSDG NWDLKLSSRL LNANEGNLLP KSTRIELTDS
FIKLIDDYIP VYKSSMQQLF LLNNIYNSLV PLSLLGVIAR EVEKIKDKER LLPIYEFNTL
LREQIKDEPA PFIYERLGEK YRHYFIDEFQ DTSVMQWQNM QPLIAHAVQS MSVDEQGGTL
MLVGDAKQAI YRWRGGDVNQ FLQLMSSQEL FFSGVNKEPL EFNWRSYDEI VNFNNDFFTF
LGNKLQSPVY NELYRNYLTQ KTSNKPGGYV QIDILKDDYL DYLDPEKLIP EVSKASSYHV
LEQIKHARTA GYLNDEICIL VRNNSLASEI ARFLELNGER VVSAESMLVS HSPKVAYLVA
LLNYIASDQP ELKYNFLLEH SLNSGTENRH DFINSLMNKS QELIFQELFD QPSLRDELSR
RSLYSFVQWL VECTAIMQKQ DARLSQFLEM VFEFSSQNQT GLTGLLQHWT TIENKLSLSG
SDTTGAIQVM TIHKSKGLEF PVVIVAGCDT KYNDLKRTSE WLRVDPNDFE GFEYLLLSMK
EECKQYPDPV PKLYERSLEQ EKLDNINVWY VAFTRSVERL YINTQKPYSK KDTMFEFLEQ
YVNDSMLLSS KEFENFTSYA LGQDEKLSAS HALDMPMYLD QFHSNSNHSG IQISTRKGQL
WSTGKDISIQ RGNLIHHYLE KLITQEDLSN VKELIHQSTT LSKDEKLELS STCEKLIAHD
EMKDYFNNKF KVLIERPIID KNGFKFIPDR VVIYKDEVTI IDYKTGKPDI SHKEQVDHYG
ILYDNMGYLV SSKVLVYLDT MTIIKW
//
