ID A0A091CMH9_FUKDA Unreviewed; 713 AA.
AC A0A091CMH9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1 {ECO:0000313|EMBL:KFO20074.1};
GN ORFNames=H920_18543 {ECO:0000313|EMBL:KFO20074.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO20074.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO20074.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO20074.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN124860; KFO20074.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091CMH9; -.
DR STRING; 885580.ENSFDAP00000017268; -.
DR eggNOG; ENOG502QVFI; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24369; ANTIGEN BSP, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24369:SF204; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 29-RELATED; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..713
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001870877"
FT TRANSMEM 422..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 190..240
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 261..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..286
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..547
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 713 AA; 78694 MW; 6A0EE784ECFB4CB1 CRC64;
MAGRGWGVLW VCVAAATLLH AGGLAHGDCW LIEGDKGFVW LAICSQNQPP YEAIPQQINS
TIVDLRLNEN RIRSVQYASL SRFGNLTYLN LTKNEIGYIE DGAFSGQFNL QVLQLGYNRL
RNLTEGMLRG LGKLEYLYLQ ANLIEVVMAS AFWECPSIVN IDLSMNRIQQ LSSGTFVGLT
KLSVCELYSN PFYCSCELLG FLRWLAAFTN TTQTYDRMQC ESPPIYSGYF LLGQGRHGHR
SILSKLQSVC TEDSYAAEVA GPRLVPGRSQ TGRSPPPPPP PEPSLGSRAD VPCGDDECFS
GDGTTPLVAL PTMATQAEAR PLIKVKQLTQ NSATITVQLP SPFNRMYTLE HYNNSKSSTV
SRLTQAQEEI RLTNLYTLTN YTYCVVSTSS GTHHNHTCLT ICLPKPPSPL GPVPSPSTAT
HYIMTILGCL FGMVLVLGAV YYCLRRRRRQ EEKHKKAASA AAASSLKKTI IELKYGPEME
APGLAPLSQG PLLGPEAVTR IPYLPAAASE VEQYKLVESG ETPKASKGNY MEVRTGEPER
RDCELGRTGP ESQSSVAEIS TIAKEVDKVN QIINNCIDAL KSESTSFQGA KSGAVSTAEP
QLVLLSEPLA TKHGFLRKAS ILEPLTRPRP RDLAYSQLSP QYHNLSYASS PEYPCRASQS
IWERLRLSRR RPKEDEEFMA AGHALRKKVQ FAKDEDLHDI LDYWKGVSAQ HKS
//
