ID   A0A091CXP6_FUKDA        Unreviewed;       627 AA.
AC   A0A091CXP6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=Coiled-coil domain-containing protein 22 {ECO:0000256|ARBA:ARBA00016694};
GN   ORFNames=H920_15933 {ECO:0000313|EMBL:KFO22645.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO22645.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO22645.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO22645.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CCDC22 family.
CC       {ECO:0000256|ARBA:ARBA00006438}.
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DR   EMBL; KN123977; KFO22645.1; -; Genomic_DNA.
DR   RefSeq; XP_010604612.1; XM_010606310.1.
DR   AlphaFoldDB; A0A091CXP6; -.
DR   STRING; 885580.ENSFDAP00000005129; -.
DR   Ensembl; ENSFDAT00000029178; ENSFDAP00000005129; ENSFDAG00000014215.
DR   GeneID; 104849772; -.
DR   CTD; 28952; -.
DR   eggNOG; KOG1937; Eukaryota.
DR   OMA; KFEQHIQ; -.
DR   OrthoDB; 9179at2759; -.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   InterPro; IPR008530; CCDC22.
DR   InterPro; IPR048348; CCDC22_CC.
DR   InterPro; IPR048349; CCDC22_N.
DR   PANTHER; PTHR15668:SF4; COILED-COIL DOMAIN-CONTAINING PROTEIN 22; 1.
DR   PANTHER; PTHR15668; JM1 PROTEIN; 1.
DR   Pfam; PF05667; CCDC22_CC; 1.
DR   Pfam; PF21674; CCDC22_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990}.
FT   DOMAIN          1..109
FT                   /note="CCDC22 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21674"
FT   DOMAIN          128..597
FT                   /note="CCDC22 coiled-coil"
FT                   /evidence="ECO:0000259|Pfam:PF05667"
FT   REGION          304..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          450..524
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        304..318
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   627 AA;  70348 MW;  814814940C5C4B8E CRC64;
     MEEADRILIH SLRQAGTAVP PDVQTLRAFT TELVVEAVVR CLRVINPAVG SGLNPLLPVA
     MSARFRLAMS LAQACMDLGY PLELGYQNFL YPSEPDLRDL LLFLAERLPT DTSEDADQPA
     GDSAILLRAI GSQIRDQLAL PWVPPLLRTP KLQRLQGSAL QQPFHTSMLV MPKLSSRGEP
     REFQASPLLL PVPTQVPGPA GRAASLLESH AVQLCQHAGQ DCPGDEDWLR RAPRLPIQGD
     PRAPRQRLQK QLAEYLRQSW GPTGTSTQAR DLGELLQAWG AGARTGAPKG SRFTHSEKFT
     FQLEPQAQTA QVTDVPATSR QPEEDMRAAQ EQELESLREQ LAGVNHSIEE VEADMKTLGI
     SLVQVETECQ QSKLSTAERE QALRLKSRAV ELLPDGAANL AKLQLVVESS AQRVIHLAGQ
     WEKHRVPLLA EYRHLRKLQD CRELESSRRM TEIQELHQSV RAAAEEARRK EEVYKQLVSE
     LETLPRDVSR LAYTQRILEI VGNIRKQKEE ITKILSDTKE LQKEINSLSG KLDRTFAVTD
     ELVFKDAKKD DAVRKAYKYL AALHENCSQL IQTIEDTGTI MREVRDLEEQ IEMEMSKKTL
     SNLEKICEDY RALRQENAGL LGRVREA
//