ID A0A091DJ22_FUKDA Unreviewed; 604 AA.
AC A0A091DJ22;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Matrilin-4 {ECO:0000313|EMBL:KFO30250.1};
GN ORFNames=H920_08378 {ECO:0000313|EMBL:KFO30250.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO30250.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO30250.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO30250.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN122459; KFO30250.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091DJ22; -.
DR STRING; 885580.ENSFDAP00000000225; -.
DR eggNOG; KOG1217; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0031012; C:extracellular matrix; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF14; MATRILIN-4; 1.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 26..205
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 378..553
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 604 AA; 66482 MW; A7DE06680AC5DA0C CRC64;
MLLLFLQPWE TQLQSIGPRC RTGPLDLVLV IDSSRSVRSF EFETMRQFLV RLVRSLDVGL
NATRVGVIQY SSQVQSVFPL GAFSRREDME LAIRDLVPLA QGTMTGLAIQ YAMNVAFSEA
EGARPLEQRV PRIAVIVTDG RPQDRVAEVA ARARARGIEI YAVGVQRADV GSLRAMASPP
LDEHVFLVES FDRIQEFGLQ FQGRLCGKDP CAEWGHGCQH QCVNAPGTFY CACNSGYKLA
ADKKRCLAID LCAEGAHGCE HHCINSPGSY FCRCQPGFVL QQDQRSCRVI DHCSFGNHSC
QHECVSTLAG PQCLCREGHD LLPDGKSCQV RDLCNGVDHG CEFQCVSEGL SYRCLCPEGR
QLHADGKSCN WCREGHVDLV LLVDGSKSVR PQNFELVKRF VNQIVDFLDV SPEGTRIGLV
QFSSRVRTEF PLGRYGSAAE VKRAVLAVEY MERGTMTGLA LRHMVEHSFS EAQGARPRAL
HVPRVGLVFT DGRSQDDISV WAARAKEEGI VMYAVGVGKA VEEELREIAS EPAELHVSYS
PDFSTMTHLL ENLKGSICPE EGIGAGTELR SLCECEGLVE FQDRTLGALE SLTQTHILWG
AGAG
//
