ID A0A091DVY4_FUKDA Unreviewed; 2935 AA.
AC A0A091DVY4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=CUB and sushi domain-containing protein 3 {ECO:0000313|EMBL:KFO35217.1};
GN ORFNames=H920_03352 {ECO:0000313|EMBL:KFO35217.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO35217.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO35217.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO35217.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; KN121850; KFO35217.1; -; Genomic_DNA.
DR STRING; 885580.ENSFDAP00000007772; -.
DR eggNOG; KOG4297; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 26.
DR CDD; cd00041; CUB; 10.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 26.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 11.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656:SF4; PROTEIN BETA CHAIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR Pfam; PF00431; CUB; 11.
DR Pfam; PF00084; Sushi; 26.
DR SMART; SM00032; CCP; 26.
DR SMART; SM00042; CUB; 10.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 26.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 11.
DR PROSITE; PS01180; CUB; 11.
DR PROSITE; PS50923; SUSHI; 26.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2859..2880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..101
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 104..165
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 167..275
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 280..337
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 339..449
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 452..511
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 513..621
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 624..684
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 686..795
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 798..858
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 860..968
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 971..1032
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1034..1067
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1078..1139
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1141..1211
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1217..1276
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1278..1386
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1389..1448
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1450..1561
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1560..1621
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1623..1734
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1734..1796
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1797..1858
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1859..1923
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1924..1981
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1982..2039
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2040..2097
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2098..2159
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2160..2217
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2221..2278
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2282..2339
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2340..2398
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2399..2458
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2459..2516
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2517..2574
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2578..2636
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2637..2696
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 2219..2238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 308..335
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 686..713
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 1952..1979
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2010..2037
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2068..2095
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2130..2157
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2188..2215
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2249..2276
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2310..2337
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2369..2396
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2487..2514
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2545..2572
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2607..2634
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 2935 AA; 320223 MW; 37E3760FFFE21CEA CRC64;
MGTVLSPDYP EGYGNNLNCI WTIISDPGSR IHLSFNDFDL ESQFDFLAVK DGNSADSPIL
GTFTGAEVPS HLTSNSHILR LEFQADHSMS GRGFNITYNT FGHNECPDPG IPINARRFGD
NFQLGSSISV ICEEGFIKTQ GTETITCILM DGKVLWSGPI PRCGAPCGGH FSAPSGVILS
PGWPGYYKDS LNCEWVIEAE PGHSIKITFE RFQTELNYDV LEVHDGPNLL SPLLGSYNGT
QVPQFLFSSS NFIYLLFTTD NSRSNNGFKI HYESVTVNTY SCLDPGIPVH GLRYGHDFSI
GSTVSFSCDP GYRLSHEEPL LCEKNHWWSH PLPTCDALCG GDVRGPSGTI LSPGYPEFYP
NSLNCTWTVD VTHGKGVQFS FHTFHLEDHH DYLLITENGS FTQPLARLTG SELPATINAG
LYGNFRAQLR FISDFSISYE GFNITFSEYN LEPCEDPGTP QYGSRVGFSF GVGDTLTFSC
SLGYRLEGAS EVICLGGGRR VWSAPLPRCV AECGASATNN EGILLSPNYP LNYENNHECI
YSIQVQAGKG INISARTFHL AQGDVLKIYD GKDKTTHLLG AFTGASMRGL TLSSTSNQLW
LEFNSDSEGT DEGFQLVYTS FELSHCEDPG IPQFGYKISD QGHFAGSTII YGCNPGYTLH
GSSLLKCMTG ERRAWDYALP SCIAECGGRF KGESSGRILS PGYPFPYDNN LRCMWMIEVD
PGNIVSLQFL AFDTEASHDI LRVWDGPPEN EMLLKEISGS LIPEGIHSTL NIVTIQFDTD
FYISKSGFAI QFSSSVATAC RDPGVPMNGT RNGDGREPGD TVVFQCDPGY ELQGQERITC
IQVENRYFWQ PSPPVCIAPC GGNLTGSSGF ILSPNFPHPY PHSRDCDWTV AVSTDYVISL
AFISFSIEPN YDFLYIHDGP DSNSPLIGSF QDSKLPERIE SSSNTMHLAF RSDGSVSYTG
FHLEYKAKLR ESCFDPGNIM NGTRLGMDYK LGSTVTYYCD AGYVLQGYST LTCIMGDDGR
PGWNRALPSC HAPCGSRSTG SEGTVLSPNY PKNYSVGHNC VYSIAVPKEF AVPRTSSTQC
SSVPEPRFGR RIGNEFAVGS LVLFECNPGY ILHGSTTIRC DTVPNSLAQW NDSLPTCIVP
CGGILTKRKG TILSPGYPEP YDNNLNCVWK ITVPEGAGIQ VQVVSFATEH NWDSLDFYDG
GDNNAPRLGS YSAIGLDSCP EPQTPSSGIK LGDRYMVGDV VSFQCDQGYS LQGHSHITCM
PGPVRRWNYP IPICLAQCGG GMSDFSGVIL SPGFPGNYPS SLDCTWTIKL PIGFGVHLHF
VNFSTETIHD YLEVRSGSSE MSTVIGRLSG PQIPSSLFST THETSLYFHS DYSQNKQGFH
IVYQAYQLQS CPDPRPFRNG FVIGNDFTVG QTISFECFPG YTLLGDSALT CLHGVSRNWN
HPLPRCEALC GGNITAMNGT IYSPGYPDEY PNFQDCFWLV RVPPGNGIYI NFTVLQTEPI
YDFITVWDGP DQNSPQIGQF SGNTALESVY STANQILIKF HSDFTTSGFF VLSYHAYQLR
VCQPPPRVAN AEILTEDDEF EIGDIIRYQC LPGFTLVGNA ILTCRLGERL QMDEAPPVCQ
VLCPANELRL DSTGVILSPG YPDSYPNLQM CAWSISVEKG YNISMFVEFF QTEKEFDVLQ
VYDGPNIQSP VLVSLSGDYS SAFNITSNGH EVFLQWSADH GNNKKGFRIR YIAFYCSTPE
SPPHGYIISQ TGGQLNSVVR WACDRGFRLV GKSSAVCKKS SYGYHAWDAP VPACQAISCG
IPKAPTNGGI LTTDYLVGTR VTYFCNDGYR LSSKELTTAT CQSDGTWSNH NKTPRCVVVT
CPSINSFTLE HGRWRIVNGS HYEYKTKVVF SCDPGYHGLG PASIECLANG TWSWRNERPY
CQIISCGELP TPPNGNKIGT QTSYSSTAIF TCDSGFMLVG SAVRECLSSG LWSGSETRCL
AGHCGIPELI VNGQVIGENY GYRDTVVYQC SPGFRLIGSS VRICQQDHNW SGQLPSCVPV
SCGHPGSPIY GRTSGNGFNF NDVVTFSCNT GYLMQGPTKA QCQANRQWSH PPPMCRVVNC
SDPGIPANSK RESKIEHGNF TYGTVVFYDC NPGYFLFGSS VLICQPNGQW DKPLPECIMI
DCGHPGVPPN AVLSGEKYTF GATVHYTCTG KRSLLGLASR TCQLNGHWSG SQPHCSGDAT
GMCGDPGTPG HGSRQESDFR SKSTVRFACD TGYIIHGSEA RTCLANGSWT GRQPECKGDA
TGMCGDPGTP GHGSRQESDF RSKSTVRFAC DTGYIIHGSE ERTCLANGSW TGRQPECKAV
QCGNPATTAN GKVFRIDGMT FSSSVIYSCM EGYILSGPSV RQCTANGTWS GSLPNCTIIS
CGDPGTPANG LRYGDDYVVG QNVSYMCQPG YTMELNGSRV RTCTTNGTWS GVMPSCRAVT
CSAPPQISNG RLEGTNFDWG FSISYICSPG YELSFPAVLT CVGNGTWSGE VPQCLPKFCG
DPGVPSQGKR EGKSFIYQSE VSFSCSSPFI LVGSSTRICQ ADGTWSGSAP HCIEPTRTSC
KNPGVPRHGS QNNTFGFQVG SVVQFHCKKG HLLQGSTTRT CLPDLTWSGV QPECIPHSCK
QPETPAHANV VGMDLPSHGY TLIYTCQPGF FLAGGTEHRV CRSDNTWTGK VPVCEAGSKI
LVKDPRPALG TPSPKLSVPD DVFAQNYIWK GSYNFKGRKQ PMTLTVTSFN ASTGRVNATL
SNSNMELLLS GVYKSQEARL MLHIYHIKVP AHASMKKMKE ENWAMDGFVS AEPDGATYVF
QGFIQGKDYG QFGLQRLGLN MSEGSNSSNQ PHGTNSSSVA IAILVPFFAL IFAGFGFYLY
KQRTAPKTQY TGCSVHENNN GQAAFENPMY DTNAKSVEGK AVRFDPNLNT VCTMV
//
