ID A0A091E8A9_FUKDA Unreviewed; 1296 AA.
AC A0A091E8A9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Roundabout like protein 3 {ECO:0000313|EMBL:KFO31391.1};
GN ORFNames=H920_07226 {ECO:0000313|EMBL:KFO31391.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO31391.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO31391.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO31391.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN122286; KFO31391.1; -; Genomic_DNA.
DR STRING; 885580.ENSFDAP00000007419; -.
DR eggNOG; KOG4222; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF37; ROUNDABOUT GUIDANCE RECEPTOR 3; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SMART; SM00406; IGv; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1296
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001872326"
FT DOMAIN 65..161
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 167..254
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 272..314
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 319..412
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 423..505
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 530..624
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 641..738
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 743..840
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 514..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..892
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 943..1296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 985..1000
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1046..1061
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1062..1076
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1120..1137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1185
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1239..1288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1296 AA; 138732 MW; 037A5ADFD3EF7E18 CRC64;
MLRYLLKALL QMNLFADSLA GDISNSSELL FGGFNSSLAA LNHSLPLPRD PAVNGSRVGP
EDAMPRIVEQ PPDLLVSRGE PATLPCRAEG RPRPNIEWYK NGARVATARE DPSAHRLLLP
SGALFFPRIV HGRRARPDEG VYTCVARNYL GAAASRNASL EVAVLREDFR QNPENVVVAV
GEPAVMECVP PRGHPEPSVT WKKDNARFKE EDGRITIRGG KLMMSHTLKS DAGMYVCVAS
NMAGERESGA AELVVLGRHW KLWSYRLGGG EWSRYEIRSD HSLWIGHVSA EDEGTYTCVA
ENSVGRVEAS SSLSVHVPPQ LVTQPQDQMA APGEDVVFQC ETKGNPPPAI FWQKEGSQVL
LFPSQSLQPT GRFSVSPRGQ LNITEVQSGD AGYYVCQAVS VAGSILAKAL LEIKGASLDG
LPPVILQGPA NQTLALGSSV WLPCRVSGNP QPSVQWRKDR QWLQGDDLRF NLMANGTLYI
ASVQEMDMGF YSCVAKSSLG EATWSGWLRK REDWGASLDP PTEPSTPPGP PSQPVVSEIT
KNSITLSWKP NPQAGATVTS YVIEAFSQAA GNTWQTVADG VQLETHTVSG LQPSTIYLFL
VRAVGAWGLS EPSPVSKPVR TKDSSPSRAA EDSWRGQYGL PEVSVRMQEP KVLGPRTLQV
SWTVDDPVQS VQGFRVSWRV AGLDGGSWTM QDLQIPSQQS TVLRGLPPGT QIQIKVQAQG
QEGLGPESPF VTGSIPEEAP SGPPQGVTVA LGGDSNSSIT VSWEPPLPSQ QNGAITEYQI
WCLGNESRFH LNRSAAGWAR SVTLRGLLPE LGVFDLLPHS SLLSPTGSFS EASFAYTPAV
SFPHSEGLSG ASSRPPMGLS PAHYPWLADS WPHPSGSPSA QETRGSCCPS NPDPEDRYYN
EAGISLYLAQ TARGTAVPGE GPVYSTIDPA GEELQTFHGG FPQHPSGDPG TWSQYAPPEW
SQGDGGARGG KVKLLGKPVQ MPSLNWPESL PPPPPSCELG CPEGPEEELV GSSESEEWRP
PMPERSHLTE LSLSGGCPMA PSRGETPSPT PSYGQQSTAT LTPSPPDPPL PPSDIPHLHQ
MPRRAPLGPS SPLSVSQPTL SSHEGRPAGL GAGPTASHHL SPSPIPSTAS SAPGATGRTL
QVPGEMTPPL QGPRARIRKK SKALPYRREH SPGDLPPPPL PPPEDEAGWA MGLRAAGSLS
SLERERSGER RVLQAVPPGA QRGPHQDEGV WLPYSRPSFL SRGQGTSTCS TAGSNSSRGS
GSSRGSRGPG RSRSQSRSRS QSQRPGQKCQ EVRTRE
//
