ID A0A091ES36_CORBR Unreviewed; 1177 AA.
AC A0A091ES36;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Voltage-dependent L-type calcium channel subunit alpha-1F {ECO:0000313|EMBL:KFO52485.1};
DE Flags: Fragment;
GN ORFNames=N302_14112 {ECO:0000313|EMBL:KFO52485.1};
OS Corvus brachyrhynchos (American crow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC Corvus.
OX NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO52485.1, ECO:0000313|Proteomes:UP000052976};
RN [1] {ECO:0000313|EMBL:KFO52485.1, ECO:0000313|Proteomes:UP000052976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO52485.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003808}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU003808}.
CC -!- SIMILARITY: Belongs to the calcium channel alpha-1 subunit (TC
CC 1.A.1.11) family. {ECO:0000256|RuleBase:RU003808}.
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DR EMBL; KK717699; KFO52485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091ES36; -.
DR STRING; 85066.A0A091ES36; -.
DR Proteomes; UP000052976; Unassembled WGS sequence.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 4.
DR Gene3D; 6.10.250.2500; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 2.
DR InterPro; IPR031649; GPHH_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR002077; VDCCAlpha1.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR45628; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR PANTHER; PTHR45628:SF2; VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1F; 1.
DR Pfam; PF16905; GPHH; 1.
DR Pfam; PF00520; Ion_trans; 5.
DR PRINTS; PR00167; CACHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 4.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PIRSR:PIRSR602077-1};
KW Calcium channel {ECO:0000256|ARBA:ARBA00022673,
KW ECO:0000256|RuleBase:RU003808};
KW Calcium transport {ECO:0000256|ARBA:ARBA00022568,
KW ECO:0000256|RuleBase:RU003808};
KW Glycoprotein {ECO:0000256|PIRSR:PIRSR602077-3};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR602077-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882,
KW ECO:0000256|RuleBase:RU003808}.
FT TRANSMEM 77..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 649..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 815..840
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 883..901
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1089..1112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..110
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 314..480
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 565..845
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 866..994
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1048..1122
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1132..1177
FT /note="Voltage-dependent L-type calcium channel IQ-
FT associated"
FT /evidence="ECO:0000259|Pfam:PF16905"
FT REGION 142..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..526
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 58
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR602077-1"
FT BINDING 428
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR602077-1"
FT BINDING 786
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR602077-1"
FT CARBOHYD 23
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000256|PIRSR:PIRSR602077-3"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO52485.1"
FT NON_TER 1177
FT /evidence="ECO:0000313|EMBL:KFO52485.1"
SQ SEQUENCE 1177 AA; 130142 MW; 3F222D0E19479AF0 CRC64;
DLESEDDPSP CAFSGHGRAC LQNNTECRGR WEGPNGGITN FDNFFFAMLT VFQCITMEGW
TDVLYWMQDA MGHELPWIYF VSLVIFGSFF VLNLVLGVLS GEFSKEREKA KARGDFQKLR
EKQQLEEDLR GYRDWITQAE DLEGDEEEGE HEKHQWGTPN SLNPWGTPNS LNTDIPKSLN
PGTPNSLDLG TPNSLNPQGT PNPPEPGNLN SLDWASPNSL NLGIPNPQDL GTPNSLDLGT
PNSLDLDTPN SLNPDIPNPP GLGTPNSLDL GTLISLNPDI PNYLNTPNSE PGHPEFPGLG
TLKFAEPRHP KPPDCFVVCG GVLETALVER GAMEPLGISV LRCVRLLRVF KVTRHWASLS
NLVGSLLNSM KSIASLLLLL FLFIIIFALL GMQLFGGRFS FDETQTKRST FDTFPQALLT
VFQILTGEDW NAVMYDGIMA YGGPVFPGML VCVYFVILFI CGNYILLNVF LAIAVDNLAD
GDNINSGGDK KDKAGESVHG PHPSPSPAQV EGDQPEEEEE EEEGSEEGEC HLRRHQGALG
GGSALMWGSL EGGVLRVKCH ALINHHIFTN LILVFIILSS VSLAAEDPVR AHSPRNHVGY
WAHWANWEGL GELGGWGQLE AHGLPQMTVF GAFLHKGSFL RNWFNLLDLL VVGVSLISFG
MHSSAISVVK ILRVLRVLRP LRAINRAKGL KVGNWEHWEA LGALGALGGG ILPAVATAGG
RLGHWLYCCT DEAKHTPGEC RGTFLVYKDG DVSHPSVRER LWLNSDFNFD NVLAGMMALF
TVSTFEGWPA SPHAAIDANA ENQGPIYNYR VEISIFFIVY IIVIAFFMMN IFVGFVIITF
RAQGESEYRN CELDKNQPLR RYIPKNRTQY RVWAMVNSTA FEYIMFVLIL LNTIALAVQG
VSHRGSHKGR SQDRGSSPPP LPQHYFCDAW NTFDALIVVG SVVDIAVTEV NSSEDSSRIS
ITFFRLFRVM RLVKLLSKGE GIRTLLWTFV KSFQVGWGGH GVQLSCGRVQ VCHRGTGVPQ
GYRCAIGAQV CHRGYRCAPG VQACPVGYRC ATGEAWQEIM LASLPGKRCD PESDAGPGEE
FTCGSNFAIA YFISFFMLCA FLIINLFVAV IMDNFDYLTR DWSILGPHHL DEFKRVWSEY
DPAAKGRIKH LDVVTLLRRI QPPLGFGKLC PHRVACK
//
