ID A0A091F7L0_CORBR Unreviewed; 1413 AA.
AC A0A091F7L0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Peroxidasin {ECO:0000313|EMBL:KFO65231.1};
DE Flags: Fragment;
GN ORFNames=N302_01845 {ECO:0000313|EMBL:KFO65231.1};
OS Corvus brachyrhynchos (American crow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC Corvus.
OX NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO65231.1, ECO:0000313|Proteomes:UP000052976};
RN [1] {ECO:0000313|EMBL:KFO65231.1, ECO:0000313|Proteomes:UP000052976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO65231.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK719741; KFO65231.1; -; Genomic_DNA.
DR STRING; 85066.A0A091F7L0; -.
DR Proteomes; UP000052976; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0140825; F:lactoperoxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd05745; Ig3_Peroxidasin; 1.
DR CDD; cd05746; Ig4_Peroxidasin; 1.
DR CDD; cd09826; peroxidasin_like; 1.
DR Gene3D; 6.20.200.20; -; 1.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR047018; Peroxidasin_Ig-like3.
DR InterPro; IPR034828; Peroxidasin_Ig-like4.
DR InterPro; IPR034824; Peroxidasin_peroxidase.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR PANTHER; PTHR11475:SF75; PEROXIDASIN HOMOLOG; 1.
DR Pfam; PF03098; An_peroxidase; 1.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00093; VWC; 1.
DR PRINTS; PR00457; ANPEROXIDASE.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SMART; SM00406; IGv; 4.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00214; VWC; 1.
DR SUPFAM; SSF57603; FnI-like domain; 1.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 4.
DR PROSITE; PS51450; LRR; 2.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
DR PROSITE; PS01208; VWFC_1; 1.
DR PROSITE; PS50184; VWFC_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR619791-2};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR619791-2};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 179..265
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 275..361
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 366..453
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 454..543
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1346..1404
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT COILED 1322..1349
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 1007
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO65231.1"
FT NON_TER 1413
FT /evidence="ECO:0000313|EMBL:KFO65231.1"
SQ SEQUENCE 1413 AA; 159484 MW; DE0FC5C38CAD2B9F CRC64;
DLRFNRIKEI QPGEFRRLKN LNTLLLNNNQ IKRIPSGAFE DLENLKYLYL YKNEIQSIDR
QAFKGLASLE QLYLHFNQIE TLEPESFTHL PKLERLFLHN NRIAHLIPGT FSHLESMKRL
RLDSNALHCD CEILWLAELL KTYAESGNAQ AAATCEYPRR IQGRSVATIT PEELNCERPR
ITSEPQDVDV TSGNTVYFTC RAEGNPKPEI IWLRNNNELS MKEDSRLNLL DDGTLMIQNT
QETDQGIYQC MAKNVAGEVK TQEVTLRYFE SPARPSFVIH PQNTEVLVGE SVTLECSATG
HPQPRITWTK GDRTPLPNDP RVTITPSGGL YIQNVKQEDS GEYTCFATNS VDNIHATAYI
IVQALPQFTV TPQDKTVIEG QTVDFPCEAK GYPQPVIAWT KGGGQLSVDR RHLVLSSGTL
RISRVALHDQ GQYECQAVNI IGSQRIVVYL TVQPRVTPVF ASVPSDMTVE VGTNVQIPCS
AQGEPEPVIT WNKDGVQVTE SGKFHVSPEG FLTIRDVGTA DEGRYECVAR NTIGYSSVSM
VLSVNVPNVS RNGDPFVQTS IVEAIATVDR AINSTRTHLF DSRPRSPNDL LALFRYPRDP
YTVEQARAGE IFERTLQLIQ DHVQDGLMVD LNGTSYHYND LVSPQYLNLI ANLSGCTAHR
RVNNCSDMCF HQKYRTHDGT CNNLQHPMWG ASLTAFERLL KSVYENGFNL PRGIEPRRLS
NGYALPMPRL VSTTLIGTET VTPDDQYTHM LMQWGQFLDH DLDLTVAALS EARFSDGQHC
SSVCTNDPPC FSIMIPPNDP RVRNGARCMF FVRSSPVCGS GMTSLLMNSV YPREQINQLT
SYIDASNVYG SSDHEALEIR DLASQRGLLR QGIVQRSGKP LLPFATGPPT ECMRDENESP
IPCFLAGDQR SNEQLGLTSI HTLWFREHNR IATELLKLNP HWDGDTIYHE TRKIVGAEMQ
HITFSHWLPK IFGEVGMKML GEYKGYDPSV NSGITNEFAT AAFRFGHTLI NPFLYRLDEN
FEPIPQGHLP LHKAFFSPFR IVNEGGIDPL LRGFFGVAGK MRVPSQLLNT ELTERLFSMA
RTVALDLAAM NIQRGRDHGI PPYHDFRVYC NLSSAQTFED LKNEIKNPDI REKLSRLYGS
PLNIDLFPAL MVEDLVPGSR LGPTLMCLLS TQFRRIRDGD RLWYENPGVF TPAQLTQIKQ
TSLARVLCDN GDNITRVQHD VFKVAEFPHG YSSCEDIPKL DLRMWQDCCE DCRTRGQFNA
FSYHFRGRRS LDYSFREDKP LKKMKTAKTV SSVKQSKYFR NATSASNENR NVPAVNDFKE
FVLEMQKTIS SLRNQIKKLE SRLSNSDCTD EEGKSYSSNE TWKRDPCTLC ECKVGQITCF
VESCPPADCE APVKGKGDCC PVCLQQNTNK KKP
//
