ID A0A091FV43_9AVES Unreviewed; 405 AA.
AC A0A091FV43;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=SH3 and cysteine-rich domain-containing protein {ECO:0000313|EMBL:KFO73069.1};
GN ORFNames=N303_10960 {ECO:0000313|EMBL:KFO73069.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO73069.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO73069.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO73069.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004278}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004278}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004278}.
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DR EMBL; KL447394; KFO73069.1; -; Genomic_DNA.
DR RefSeq; XP_009554964.1; XM_009556669.1.
DR AlphaFoldDB; A0A091FV43; -.
DR STRING; 55661.A0A091FV43; -.
DR GeneID; 104055540; -.
DR KEGG; cuca:104055540; -.
DR CTD; 6769; -.
DR OrthoDB; 3716527at2759; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20880; C1_Stac1; 1.
DR CDD; cd11833; SH3_Stac_1; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR039688; STAC1/2/3.
DR InterPro; IPR035508; STAC1_SH3.
DR PANTHER; PTHR15135:SF3; SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15135; STAC; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF16664; STAC2_u1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR PRINTS; PR01887; SPECTRNALPHA.
DR SMART; SM00109; C1; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50002; SH3; 2.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 109..161
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 288..347
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 350..405
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 45425 MW; 204AF6A6A9CCC23B CRC64;
MIPPSSTTEV SVDSVEKENE GESTEQPPSP ASTTSQESKL QKLKRSLSFK TKSLRSKSAD
NFFQRTNSDV KLQVELVPEV STSTGQLPSS ESQASSPTRA QQLPENNKTH IFQEHIFKKP
TFCDVCNHMI VGTNAKHGLR CKACKMSIHH KCTDSIGQQR CMGKLPKGFR RYYSSPLLIH
EQFGCIKEVM PIACGNKVDP VYETLRFGTS LAQKTKKGSS GSGSESPNRN STADLAQVPE
EGNSSAGTLD ISRKRSNSVF TYTENGTEHF GEEPKNIHSP GPFYKSTLQM NTYVALYKFV
PQENEDLEMR PGDMITLLED SNEDWWKGKI DDRIGFFPAN FVQRVQHDEK IYRCIRTFIG
CKEQGQITLK ENQICVTSEK EHDGFIKVYS GKKKGFVPID VLENI
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