ID   A0A091G9G8_9AVES        Unreviewed;      1007 AA.
AC   A0A091G9G8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE   Flags: Fragment;
GN   ORFNames=N303_00991 {ECO:0000313|EMBL:KFO78001.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO78001.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO78001.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO78001.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; KL447850; KFO78001.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091G9G8; -.
DR   STRING; 55661.A0A091G9G8; -.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd22095; F-box_FBXO18; 1.
DR   CDD; cd18786; SF1_C; 1.
DR   Gene3D; 1.20.1280.50; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF30; F-BOX DNA HELICASE 1; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF12937; F-box-like; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SUPFAM; SSF81383; F-box domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760}.
FT   DOMAIN          190..239
FT                   /note="F-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50181"
FT   REGION          17..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          120..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..141
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO78001.1"
FT   NON_TER         1007
FT                   /evidence="ECO:0000313|EMBL:KFO78001.1"
SQ   SEQUENCE   1007 AA;  114209 MW;  72CED368FB531BEB CRC64;
     KRFKKTHLTA TDCEALAQSP EGSSSLTQPL SQRRSRGDVN RGLHPTHWTR RHPGGQGQQK
     SITDYFRISE TRVGAGGMKN SGIKEELLDL IFAESDDSFS TVMEMSGESR SFLTGEDLLS
     TPRESSRKRH LSTASVHKQE HDLWSEPEKK TMLVHPEHIQ IKQELDDMDI EPVPDAHYGL
     LGTRNWEVPQ GSIDELPIEV LRHIFAFLPV TDLYQNLSLV CRCWREIVVD PLFIPWKKLY
     HQYLMKEDAA LHRVEQVLQD FAITKEQEAC VLGLIRCVSA IPTAPKVDPS VVLRCLKSHH
     LFPKAEVCIA NKLPHLQSRM GPENMWAIIA VMVLFSDGVR DIRNLMVCLQ RPCSNLSVVD
     VTERLYCIAT LLYAMRDRNI AITNRIHYNI FYCLYLMENA SITTQTVEEE TPASRYRQDL
     WASCPEVKLT HEQKRILNHK IERGQIVKIM AFAGTGKTST LLKYAEKFAD MNFLYVAFNK
     AVVEKGKSVF PRNVMCKTFH SLAFGSVGKR YKEKGKLNFS KMSAYSISSL IQNREGQSLF
     IRGKTVLQTL ESFFASSDEE ICEEHTPIWF KNTHGERKLV SREEKKIIVE EAREIWHKMK
     KLDGDVEKKY KMTCDGYLKL WQLSKPHLSG YDAIFVDEAQ DCTPAIVDIV LSQTCGIILV
     GDPHQQIYTF RGAVNTLYSV LHTHVYYLTQ SFRFGPEIAY VGATILDVCK RIRNKTLVGG
     NQKGDVRGTI GGKITMLSRS NFNVFEDAVK LTGRERPIKI HVIGGLARFG LSKIYDIWKL
     SQPADERKKA NLVINDSFIK KWEETQGFLG LREYAERIDD KDLEAKIAIV EKYKERIPEL
     VQKTERSHVS QEAVADYLIG TVHQAKGLEF DTVLIGDDFV NVPCLGGNQR RINFSVGMYP
     EDEWNLLYVA VTRAKKHLLM SKSLEHLLAL AGECFLRVEL MSEAAKDGAT VVCSVPQCTG
     TAQSQLVVKK LPLTHSNGSR DVGGYLCHTC TQKHFGSLTP LTFIPAL
//