ID A0A091GEX7_9AVES Unreviewed; 512 AA.
AC A0A091GEX7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Putative glycerol kinase 5 {ECO:0000256|ARBA:ARBA00013787};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase 5 {ECO:0000256|ARBA:ARBA00033026};
DE Flags: Fragment;
GN ORFNames=N303_02438 {ECO:0000313|EMBL:KFO79886.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO79886.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO79886.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO79886.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate;
CC Xref=Rhea:RHEA:21644, ChEBI:CHEBI:15378, ChEBI:CHEBI:17754,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:57597, ChEBI:CHEBI:456216;
CC EC=2.7.1.30; Evidence={ECO:0000256|ARBA:ARBA00001373};
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR EMBL; KL448071; KFO79886.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091GEX7; -.
DR STRING; 55661.A0A091GEX7; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07793; FGGY_GK5_metazoa; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR037444; GK5_FGGY.
DR PANTHER; PTHR10196:SF68; GLYCEROL KINASE 5-RELATED; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:KFO79886.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 11..272
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 282..466
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO79886.1"
FT NON_TER 512
FT /evidence="ECO:0000313|EMBL:KFO79886.1"
SQ SEQUENCE 512 AA; 57132 MW; 775358D19DEC0636 CRC64;
PGSSRGPARF VLGVDVGSTV LKCHVYDREA AVRGSACRKV ESLYPCPGWV ELDPEVLWSQ
FVVVIKEAVQ AAGLHMRQIA GLGISAQRAT FITWHKRTGK PFHNFISWQD LRSAELVNSW
NRSFLLKVIH VIFTVLHFLT RSDRYLAPSF LTFSTHQTSM KLSWVFKNIH EAEEAAKRNN
CCFGTVDTWL LYRLTKGSVY ATDYSNASAT GIFDPFTKCW NSGLCYLLSI PMSIYPSVKD
TSFNFGSADS EIFGVPVPIM AMVADQQAAV FGECCFHPGD VKVTMGTGGF WNVNTGDHLF
ASQRDLYPLI GWKIGEEVVY LTEGCMTDIG TAIKWAQDTS LFTNVDETEK MARSVVDSGG
VCFVPGFQAS VNDPYLCASF TGLKPCTTRN HLVRAILESV AFRNKQLYDI IVKKVRIPLQ
TIRADGGVSN NSFVMQMTSD LINKKIEKPA NADMSSLGAA FLAGLASGFW TDKEQLKKLR
RIEAVFEPQK DFEEYRPALD TWLQAIKHSP HW
//
