ID   A0A091H0S0_9AVES        Unreviewed;       553 AA.
AC   A0A091H0S0;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Steryl-sulfatase {ECO:0000313|EMBL:KFO79927.1};
DE   Flags: Fragment;
GN   ORFNames=N303_15222 {ECO:0000313|EMBL:KFO79927.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO79927.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO79927.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO79927.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC       {ECO:0000256|ARBA:ARBA00008779}.
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DR   EMBL; KL448073; KFO79927.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091H0S0; -.
DR   STRING; 55661.A0A091H0S0; -.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd16159; ES; 1.
DR   Gene3D; 3.30.1120.10; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   Gene3D; 1.10.287.550; Helix hairpin bin; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR024607; Sulfatase_CS.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR42693:SF9; STERYL-SULFATASE; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   Pfam; PF14707; Sulfatase_C; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
DR   PROSITE; PS00149; SULFATASE_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        162..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        191..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          3..388
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO79927.1"
FT   NON_TER         553
FT                   /evidence="ECO:0000313|EMBL:KFO79927.1"
SQ   SEQUENCE   553 AA;  62383 MW;  D650BA2042DE7C9A CRC64;
     SNPNFVLLMA DDLGIGDLGC YGNKTLRTPN IDRLAEEGVT LTQHIAASPL CTPSRAAFLT
     GRYPIRSGMA SFSRVGVFLF SASSGGLPSE EITFSRLLKQ RGYATALIGK WHLGMNCESS
     NDFCHHPLSH GFDYFYGLTV TNLRDCKPGQ GSVFLKGVQK SLVIPMQIAG IALMSLAIVQ
     YIGLFNIPFQ ALGYCMLITA ISLAVLTFFF YHFRHLNCFL MRNHQIIQQP LSYENLTQRL
     TKEAVQFIER NTEAPFLLVL SYLHVHTALY ASKNFRGKSK HGLYGDAVEE MDWSVGQVLD
     VLEKYNLSNK TLVYFTSDQG AHVEEISSSG EVHGGYNGIY KGGKSMNWEG GIRVPGLLCW
     PGVIQAGAYI DEPTSNMDIF PTIVKLAKAQ LPSDRIIDGH DLMPLLQGKV TRSKHEFLFH
     YCNAYLNAVR WHPRNSESVW KVFFFTPNFS PEDSNGCYDD HVCFCHGGFI TWHDPPLLFD
     LSRDPEEKVP LTPETESRFY EILRVIHLEV DNHSRSLHAV PDQLSWDNLL WKPWLQLCCS
     SFFQSCYCDY DSE
//