ID A0A091H489_9AVES Unreviewed; 1181 AA.
AC A0A091H489;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Integrin alpha-11 {ECO:0000313|EMBL:KFO81122.1};
DE Flags: Fragment;
GN ORFNames=N303_01903 {ECO:0000313|EMBL:KFO81122.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO81122.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO81122.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO81122.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
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DR EMBL; KL448190; KFO81122.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091H489; -.
DR STRING; 55661.A0A091H489; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd01469; vWA_integrins_alpha_subunit; 1.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 2.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF21; INTEGRIN ALPHA-11; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR01185; INTEGRINA.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00191; Int_alpha; 5.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 3.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51470; FG_GAP; 6.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003762};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU003762}.
FT TRANSMEM 1135..1159
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 13..71
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 80..140
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 153..334
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REPEAT 344..395
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 455..516
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 517..575
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 579..639
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO81122.1"
FT NON_TER 1181
FT /evidence="ECO:0000313|EMBL:KFO81122.1"
SQ SEQUENCE 1181 AA; 132529 MW; 52359DB03A86432A CRC64;
LSSGFSNTFN IDTKRPKIIA GSKEAYFGYT VQQHDIGGKK WLVVGAPYET NGQQKTGDVY
KCPVTSDTHN NCTKLNLGRV TLSNVSERKD NMRLGLSLAT NPKDNSFLAC SPLWSHECGS
SYYTTGMCSR VNSNFRFSKT VAPALQRCQT YMDIIIVLDG SNSIYPWVEV QHFLINILKK
FYIGPGQIQV GVVQYGEDVV HEFHLNDYRS VKDVVAAASH IEQRGGTETR TAYGIEFARS
EAFQKGGRKG AKRVMIVITD GESHDSPDLE KVIEDSEKDN VTRYAVAVLG YYNRRGINPE
AFLNEIKFIA SDPDDKHFFN VTDEAALKDI VDALGERIFS LEGTNKNEIS FGLEMSQTGF
SSHVVEDGIL LGAVGAYDWN GAVLKETSSG KVIPLRESYL QEFPEELKNH GAYLGYTVSS
VISTKHERIY VAGAPRFNHT GKVIIFSMHN NRNLTIHQAL KGEQIGSYYG SEINSLDVNG
DGVTDVLLVG APMYFSEGRE RGKVYVYTLR ENHFISSGAL IDLQSYQNSR FGSCIAAVPD
LNQDSYNDLV VGAPLEDEHQ GAIYIFLGFK ETILKKYKQR IAAMDLAPGL MYFGCSIHGQ
LDLNEDGLID LSVGSLGNAV LLWSRSVVQI NASIRFDPSK INIFTKDCKR NGKDATCMSA
FICLTAVFLS AHFQTASVAL RYNATIDERR YTPRAYLDES GERHTQKGLV LSAGQEHCDR
LQFHVLDTAD YVKPVTFSID YELEHPENGP MLDDGWPTSL KVSVPFWNGC NEDEHCVPDL
VLDARSDVPS AMEYCRRALR RAPTDCSAFT LSFDASVFVI ESSRRRVAVE ATLENRGENA
YSTVLNISFS RNLQFASLIP KDDTDINIDC MTEDKNPNKK VCNVSYPFFR AKAKVSFRLD
FEFSKSIFLQ SMEIYLIANS DSEEKESTKE DNFAHLNFHL KYEADLLFTR TSSLDYYEIR
SNNSLERYNS IGPPFHCIFK LQNLGFFPVE GVTIKLTIPV ATRAGNRLLL LNSFMVDQLL
LQENTTCNIW GNTTDYRRTP AEEDLSRIPH LNHSNSDIIS IDCNVKLAPN EEMNLHLHGN
LWMKSLKALK FKSLKITMTA ALQRRFGSPF VFREEDPSRQ ITFEISKPEE SQIPIWIILG
STLGGLLLLA LLVLALWKLG FFKSGSHRRA AERERNTQGL E
//
