ID   A0A091H7Y0_9AVES        Unreviewed;       734 AA.
AC   A0A091H7Y0;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Threonine synthase-like 1 {ECO:0000313|EMBL:KFO82347.1};
DE   Flags: Fragment;
GN   ORFNames=N303_01966 {ECO:0000313|EMBL:KFO82347.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO82347.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO82347.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO82347.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR604450-51};
CC   -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC   -!- SIMILARITY: Belongs to the threonine synthase family.
CC       {ECO:0000256|ARBA:ARBA00005517}.
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DR   EMBL; KL448311; KFO82347.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091H7Y0; -.
DR   STRING; 55661.A0A091H7Y0; -.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd00464; SK; 1.
DR   CDD; cd01560; Thr-synth_2; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR   HAMAP; MF_00109; Shikimate_kinase; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   InterPro; IPR031322; Shikimate/glucono_kinase.
DR   InterPro; IPR000623; Shikimate_kinase/TSH1.
DR   InterPro; IPR029144; Thr_synth_N.
DR   InterPro; IPR037158; Thr_synth_N_sf.
DR   InterPro; IPR004450; Thr_synthase-like.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   NCBIfam; TIGR00260; thrC; 1.
DR   PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR   PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR   Pfam; PF01202; SKI; 1.
DR   Pfam; PF14821; Thr_synth_N; 1.
DR   PRINTS; PR01100; SHIKIMTKNASE.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR604450-51};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760}.
FT   DOMAIN          238..309
FT                   /note="Threonine synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14821"
FT   MOD_RES         342
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
FT   NON_TER         734
FT                   /evidence="ECO:0000313|EMBL:KFO82347.1"
SQ   SEQUENCE   734 AA;  81623 MW;  8B94D43E245B1415 CRC64;
     MFHVVQYRPL IIQKNLSSMC LKLMFSRPVA FAEIWKSWFS SHSLVGNKNI ILMGLPGAGK
     TTVGRIVGQK LDCPVIDIDD NVLEATWNMS VSEKLKDVGN EQFLEEEGKA LLKFSASGSV
     ISLTGSNPMH SAAMQHMKKN GIVVYLDVPT PVILSRLKSM KVDRIVSQSP GISLKDILQF
     RKQFYKRWYD IRVLCGWDIA AEVAEKVLDA VKKYQNSELE SFISTRSSAS GRSMEKDSCK
     YFSDVVTEGL APDGGLFVPK RGLPKFTAGE WQSLIESTYI ERAQVILERC IHPADIPASK
     LAEIIGTAYG ENFTCSKIAP VRHLTGNQFL LELFHGPTAS FKDFALQMVP HIFAYCIPRS
     CNYLILVATS GDTGSAVLDG FSRLHDADKQ RIAVMNFFPE NGVSPIQKSQ MIGCQKENAW
     SVGVKSDFDF CQTAIKQIFT NSDYTGFLTV EYGTALAAAN SINWARLLPQ IVYHASAYLD
     LVHQDIIPFG SPVDVCIPTG NFGNILAALY AKMMGIPIRK CICASNENNV LTDFIRTGVY
     DLRGRKIIPT FSPAVDILKS SNLERYLHLI ANEDGQLVTQ LYNQLENKGH FQLEKDLLEK
     LQQDLVAGWC SEEDCLAAIH SVYSTTGYIL DTHTAVAKVV ADRLQDRTCP VIISSTAHYS
     KFAPAILRAL RIAEIKQNPL SQLHLLSSYS PLPPVHWGLL ETLKKTGNED HQVCAADMSM
     LMSHIETLIQ NHFM
//