ID A0A091HVG0_CALAN Unreviewed; 1678 AA.
AC A0A091HVG0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Complement C5 {ECO:0000313|EMBL:KFO99132.1};
DE Flags: Fragment;
GN ORFNames=N300_09376 {ECO:0000313|EMBL:KFO99132.1};
OS Calypte anna (Anna's hummingbird) (Archilochus anna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC Trochilidae; Calypte.
OX NCBI_TaxID=9244 {ECO:0000313|EMBL:KFO99132.1, ECO:0000313|Proteomes:UP000054308};
RN [1] {ECO:0000313|EMBL:KFO99132.1, ECO:0000313|Proteomes:UP000054308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N300 {ECO:0000313|EMBL:KFO99132.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; KL217813; KFO99132.1; -; Genomic_DNA.
DR STRING; 9244.A0A091HVG0; -.
DR MEROPS; I39.952; -.
DR Proteomes; UP000054308; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00017; ANATO; 1.
DR CDD; cd02896; complement_C3_C4_C5; 1.
DR Gene3D; 1.50.10.20; -; 1.
DR Gene3D; 2.20.130.20; -; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.1540; -; 1.
DR Gene3D; 2.60.40.1930; -; 3.
DR Gene3D; 2.60.40.1940; -; 1.
DR Gene3D; 6.20.50.160; -; 1.
DR Gene3D; 2.60.40.690; Alpha-macroglobulin, receptor-binding domain; 1.
DR Gene3D; 1.20.91.20; Anaphylotoxins (complement system); 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR009048; A-macroglobulin_rcpt-bd.
DR InterPro; IPR036595; A-macroglobulin_rcpt-bd_sf.
DR InterPro; IPR011625; A2M_N_BRD.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR000020; Anaphylatoxin/fibulin.
DR InterPro; IPR018081; Anaphylatoxin_comp_syst.
DR InterPro; IPR041425; C3/4/5_MG1.
DR InterPro; IPR048843; C5_CUB.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR002890; MG2.
DR InterPro; IPR041555; MG3.
DR InterPro; IPR040839; MG4.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR11412:SF83; COMPLEMENT C5; 1.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF07703; A2M_BRD; 1.
DR Pfam; PF07677; A2M_recep; 1.
DR Pfam; PF01821; ANATO; 1.
DR Pfam; PF21309; C5_CUB; 1.
DR Pfam; PF17790; MG1; 1.
DR Pfam; PF01835; MG2; 1.
DR Pfam; PF17791; MG3; 1.
DR Pfam; PF17789; MG4; 1.
DR Pfam; PF01759; NTR; 1.
DR Pfam; PF07678; TED_complement; 1.
DR SMART; SM01360; A2M; 1.
DR SMART; SM01359; A2M_N_2; 1.
DR SMART; SM01361; A2M_recep; 1.
DR SMART; SM00104; ANATO; 1.
DR SMART; SM00643; C345C; 1.
DR SUPFAM; SSF49410; Alpha-macroglobulin receptor domain; 1.
DR SUPFAM; SSF47686; Anaphylotoxins (complement system); 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS01178; ANAPHYLATOXIN_2; 1.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 692..727
FT /note="Anaphylatoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS01178"
FT DOMAIN 1534..1678
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO99132.1"
FT NON_TER 1678
FT /evidence="ECO:0000313|EMBL:KFO99132.1"
SQ SEQUENCE 1678 AA; 188505 MW; 0A601914468D0805 CRC64;
LLFSGTTFSQ EKTYVLTAPK IFRAGASQKV VVQAFGYEKE FPVKIAIRSF PDKLAVYSSS
HISLTPANKF QDAVTLRLQP TDLPRTENSA NYVYLEAVSP HFTRLKKIPV SYENGFLFIH
TDKPIYTPDQ SVKVRVYSLD EELQPARRET VLTFVDPEGV KVDIIEEEDF TGIVSFPDFK
IPPNPKYGIW KIEAKYKKNF ITSAVAKFEV KEYAMPSFSI VIEPERNFIS SDKFENFRIV
VKASYFYNKK LASADVFLRF GIIEETEKRM MPRSLHVTRI ENGVAEINFN SKEAVSSIGF
QSLEELDGSY LYIAASVLET TGGLSGEAEF AGVRFAVSPY KLSLIATPLF VKPGLPFFIK
VQVKDTMDQF VRNVPVTVTA KSFSEQMDET ELISEASDSG RRQTSINDGT ALFVVNIPSD
SKKLEFQVKT ADPRLSDENQ ASKIYEAKAY SSLSQSYLYI DWASNHKILE VGDFININVY
PRSHYIHKIH HFSYLITSKG KIVGFGTQDR IKDLEYDHLT FQITQEMVPS ARLVVYYIVM
GEETAELVAD SVWLNVEQKC GNSLDIKLQS SKKILNPAEV VSLNMKTQFN SFVALSSIDK
AVYGVTGRGK RAMEKVMLHL EKSDLGCGAG GGWNNVDVFR MAGLTFLTNA NADDSNEADE
TCNEILRTKR SDFKERILKE ASKYLHPEIR KCCMAGVRAY PVTETCSDRA QRIRSHARCI
SAFKDCCEFA NRLREEEPNK LLILARMHFE ALLELDEADV RSYFPESWLW EVHQVSPRYF
FSQISYQSKT LTVTLPDSLT TWEVQAVGIS DKGICVAAPL EMEVVKDIFL NIYVPYSVVR
GEQIELKGSV YNHRASAIKF CVTIATGNGI CSFGDSAARG SRMHNCQIKN LDGGSSSPVT
FRILPLELGL HTVNFTLLAA TDSETVVKTL RVMPEGITKE LHSGFTLDPQ GVYGSIKRRE
EFRYKVPLNL VPKTKIDRSV SVKGHLMGEA VATILSPSGL SALTNLPKGS AEAELMSIAP
VFYVFHYLEA SENWHLLGPE TLTSRTQMRR KMKEGIVSIS SFRNSDFSYS MWKNGQASTW
LTAFALRILG QVNQYINLDE ISVCNSLLWL IENCQMPDGS FSEFSNYQPV KLQGTLPKET
KENSLYLTAF SVIGIEKSIK ICPTQKIHDA KNKAGNYLMK NVQSAQSPFT MAITSYALAL
VDPNHHSARS AFSALKREAS VIGDPPLYRF WKDTFKAVDT HTPSSATAQM VETTAYALLT
TLLRGDQNYA NPIIKWLSEQ QRYGGGFYST QDTITALEAL TEYSLLTKRL YLDMSVKVAY
KNHGNLQLFK LTEDNFVGRT VTVPLDDDIY VSTGSSTGIA TVNVRTVYNT IGTSEESCNF
DLKILPKRHD GHRKEEGEPL GRLEACAKYR PSAREPRSGS AHAVMDIGLV SGLEANTEDL
STLASGVDQL IADYEIKDGH VILQIDSVPA DNFLCVGFRI SELFHVGMLN PATFTVYEYH
APDKRCTILY NPYGNERLVR LCEGDECKCM EAECSKMQER LDLSVTADTR REAACQNDIA
YVYKVNILSR SEEGYFVKYS ASLMDLYKRG QAFAQKNNEI TFVKKKTCTD VELSPGEQYL
IMGKEALKIN VGFKFKFQYP LDSSTWIEWW PSNPACTFCQ EFLNTMEDFA EDLIISGC
//
