ID A0A091I3S3_CALAN Unreviewed; 461 AA.
AC A0A091I3S3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Growth/differentiation factor 9 {ECO:0000256|ARBA:ARBA00017637};
GN ORFNames=N300_11012 {ECO:0000313|EMBL:KFP02123.1};
OS Calypte anna (Anna's hummingbird) (Archilochus anna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC Trochilidae; Calypte.
OX NCBI_TaxID=9244 {ECO:0000313|EMBL:KFP02123.1, ECO:0000313|Proteomes:UP000054308};
RN [1] {ECO:0000313|EMBL:KFP02123.1, ECO:0000313|Proteomes:UP000054308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N300 {ECO:0000313|EMBL:KFP02123.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer or heterodimer (Potential). But, in contrast to
CC other members of this family, cannot be disulfide-linked.
CC {ECO:0000256|ARBA:ARBA00026064}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; KL218086; KFP02123.1; -; Genomic_DNA.
DR RefSeq; XP_008493681.1; XM_008495459.1.
DR AlphaFoldDB; A0A091I3S3; -.
DR STRING; 9244.A0A091I3S3; -.
DR GeneID; 103529942; -.
DR CTD; 2661; -.
DR OrthoDB; 5301288at2759; -.
DR Proteomes; UP000054308; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19403; TGF_beta_GDF9; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR015617; Growth_differentiation_fac-9_C.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF19; GROWTH_DIFFERENTIATION FACTOR 9; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 327..461
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 288..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..336
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 52275 MW; 3CDA3F2F077C1639 CRC64;
MESTWRICVC VYCCLHWFSS NIQCSPHSRA HPSSAKTSGF LGAPKGTASD LNPLLQLPRS
VRGGYALLPP LLKVLSDRGQ QSWASESPRL QPDSRALRYM KRLYKMSATK EGIPKANKSH
LYNTVRLFTP CLECEHPPRD LRKGDVHSVD LLFNLDRVTA LEHLLKSVLL YSFDTSIPVS
SSIRCLCRLA VKEQGSSSQV CPSLSHSPAF SLHFEARKRR WLEMDVTSFL QPLIATHRRN
IHMALNFTCL LGDPQHSTKL VTPLNTALVP PSLLLYLNDT SEQAHHRWNS LGHRRTNPAW
PRPGDSPRLD PTGDQGHEDS QGKRASRRRR EEHPKGAPSA TPPYNLSQYF KQFVFPQNEC
ELHSFRLSFS QLKWDKWIIA PHRYSPQYCK GDCPRVVGHR YGSPVHTMVQ NIIYEKLDPS
VPKPSCVPAE YSPLSVLTIE PDGSIVYKEY EDMIATKCTC R
//
