ID A0A091NI96_9PASS Unreviewed; 330 AA.
AC A0A091NI96;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Pseudouridine synthase I TruA alpha/beta domain-containing protein {ECO:0000259|Pfam:PF01416};
DE Flags: Fragment;
GN ORFNames=N310_07158 {ECO:0000313|EMBL:KFP78695.1};
OS Acanthisitta chloris (rifleman).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Acanthisittidae;
OC Acanthisitta.
OX NCBI_TaxID=57068 {ECO:0000313|EMBL:KFP78695.1, ECO:0000313|Proteomes:UP000053537};
RN [1] {ECO:0000313|EMBL:KFP78695.1, ECO:0000313|Proteomes:UP000053537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N310 {ECO:0000313|EMBL:KFP78695.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC {ECO:0000256|ARBA:ARBA00009375}.
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DR EMBL; KK834047; KFP78695.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091NI96; -.
DR Proteomes; UP000053537; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0031119; P:tRNA pseudouridine synthesis; IEA:InterPro.
DR CDD; cd02568; PseudoU_synth_PUS1_PUS2; 1.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR001406; PsdUridine_synth_TruA.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR041708; PUS1/PUS2-like.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR NCBIfam; TIGR00071; hisT_truA; 1.
DR PANTHER; PTHR11142; PSEUDOURIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11142:SF4; PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000053537};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 165..267
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
FT ACT_SITE 72
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR641708-1"
FT BINDING 127
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR641708-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP78695.1"
FT NON_TER 330
FT /evidence="ECO:0000313|EMBL:KFP78695.1"
SQ SEQUENCE 330 AA; 37909 MW; 23449797181E818F CRC64;
EDQSKKTPKR KIVLLMAYSG KGYHGMQRNV GSSQFKTIED DLVSALVQSG CIPENHGEDM
KKMSFQRCAR TDKGVSAAGQ IVSLKVRLID DILEKINNHL PSHIRILGLK RVTGGFNSKN
KCDARTYSYM LPTFAFAHKD HDVQEELYRL DKETLERVNK LLSCYKGTHN FHNFTSQKGP
RDPSAKRYIM EMYCGEPFVR ENMEFAVIKV KGQSFMMHQI RKMIGLVIAI VKGYAAESIL
ERSWGEEKVD VPKAPGLGLV LERVHFEKYN RRFGNDGLHE PLEWTEEEEK IAVFKEQYIY
PTIINTEREE KSMANWLNTL PIHDFNSSAV
//
