ID A0A091PIQ0_LEPDC Unreviewed; 431 AA.
AC A0A091PIQ0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Kringle-containing protein marking the eye and the nose {ECO:0000256|ARBA:ARBA00032328};
DE Flags: Fragment;
GN ORFNames=N330_06504 {ECO:0000313|EMBL:KFQ07520.1};
OS Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae; Leptosomus.
OX NCBI_TaxID=188344 {ECO:0000313|EMBL:KFQ07520.1, ECO:0000313|Proteomes:UP000053001};
RN [1] {ECO:0000313|EMBL:KFQ07520.1, ECO:0000313|Proteomes:UP000053001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N330 {ECO:0000313|EMBL:KFQ07520.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00121}.
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DR EMBL; KK674232; KFQ07520.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091PIQ0; -.
DR PhylomeDB; A0A091PIQ0; -.
DR Proteomes; UP000053001; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00108; KR; 1.
DR Gene3D; 2.40.20.10; Plasminogen Kringle 4; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR017076; Kremen.
DR InterPro; IPR000001; Kringle.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR018056; Kringle_CS.
DR InterPro; IPR038178; Kringle_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR002889; WSC_carb-bd.
DR PANTHER; PTHR24269; KREMEN PROTEIN; 1.
DR PANTHER; PTHR24269:SF13; KREMEN PROTEIN 1; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF00051; Kringle; 1.
DR Pfam; PF01822; WSC; 1.
DR PIRSF; PIRSF036961; Kremen; 1.
DR PRINTS; PR00018; KRINGLE.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00130; KR; 1.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS00021; KRINGLE_1; 1.
DR PROSITE; PS50070; KRINGLE_2; 1.
DR PROSITE; PS51212; WSC; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR036961-50};
KW Kringle {ECO:0000256|ARBA:ARBA00022572, ECO:0000256|PROSITE-
KW ProRule:PRU00121}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053001};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT TRANSMEM 350..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..85
FT /note="Kringle"
FT /evidence="ECO:0000259|PROSITE:PS50070"
FT DOMAIN 87..181
FT /note="WSC"
FT /evidence="ECO:0000259|PROSITE:PS51212"
FT DOMAIN 185..292
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DISULFID 3..85
FT /evidence="ECO:0000256|PIRSR:PIRSR036961-50"
FT DISULFID 26..66
FT /evidence="ECO:0000256|PIRSR:PIRSR036961-50"
FT DISULFID 55..80
FT /evidence="ECO:0000256|PIRSR:PIRSR036961-50"
FT DISULFID 93..157
FT /evidence="ECO:0000256|PIRSR:PIRSR036961-50"
FT DISULFID 118..138
FT /evidence="ECO:0000256|PIRSR:PIRSR036961-50"
FT DISULFID 122..140
FT /evidence="ECO:0000256|PIRSR:PIRSR036961-50"
FT DISULFID 161..169
FT /evidence="ECO:0000256|PIRSR:PIRSR036961-50"
FT DISULFID 185..211
FT /evidence="ECO:0000256|PIRSR:PIRSR036961-50"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ07520.1"
FT NON_TER 431
FT /evidence="ECO:0000313|EMBL:KFQ07520.1"
SQ SEQUENCE 431 AA; 48109 MW; 0BA084938E470D33 CRC64;
PECYTANGAD YRGTQNQTSQ YAGKPCLFWN ETFEHPYNTL KYPNGEGGLG EHNYCRNPDG
DVSPWCYIAE HEDGIYWKYC EIPSCRMPGN LGCYKDHGEP PPLTGTSETS NKLTIQTCIS
SCRSQQFKFA GMESGYACFC GNNPDYWRYG EAASTECNSV CFGDHTQPCG GDGRVILFDT
LIGACGGNYT SATAVIYSPD FPDTYGTGKV CYWTIQVPGA SRIHFSFALF EIKDATDMVE
LLDGYTYDVL ARFNGKNRPP HTFNISLDFV ILYFFSDEIN QAQGFAIRYR AVKDNVHQNK
IPMNQTLSEK INEQANVSIN AARSSKILYV ITTSPSHPSS AMPGNITRKW WTIYSLTALL
ILSVTAIIAK IFLHITMRSH RIPSATETED SSEVTTAGEI WSIFYQPSTS ISIFKKKLRS
QQDDCNPLVG N
//
