ID A0A091QNT4_MERNU Unreviewed; 720 AA.
AC A0A091QNT4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 03-MAY-2023, entry version 30.
DE SubName: Full=X-ray repair cross-complementing protein 5 {ECO:0000313|EMBL:KFQ28286.1};
DE Flags: Fragment;
GN ORFNames=N331_03663 {ECO:0000313|EMBL:KFQ28286.1};
OS Merops nubicus (Northern carmine bee-eater).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ28286.1, ECO:0000313|Proteomes:UP000052967};
RN [1] {ECO:0000313|EMBL:KFQ28286.1, ECO:0000313|Proteomes:UP000052967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ28286.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ku80 family.
CC {ECO:0000256|ARBA:ARBA00007726}.
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DR EMBL; KK702623; KFQ28286.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091QNT4; -.
DR Proteomes; UP000052967; Unassembled WGS sequence.
DR GO; GO:0043564; C:Ku70:Ku80 complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0042162; F:telomeric DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR CDD; cd00873; KU80; 1.
DR Gene3D; 1.10.1600.10; -; 1.
DR Gene3D; 2.40.290.10; -; 1.
DR Gene3D; 1.25.40.240; Ku, C-terminal domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR InterPro; IPR024193; Ku80.
DR InterPro; IPR005160; Ku_C.
DR InterPro; IPR036494; Ku_C_sf.
DR InterPro; IPR005161; Ku_N.
DR InterPro; IPR014893; Ku_PK_bind.
DR InterPro; IPR016194; SPOC-like_C_dom_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR PANTHER; PTHR12604:SF4; X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5; 1.
DR Pfam; PF02735; Ku; 1.
DR Pfam; PF03730; Ku_C; 1.
DR Pfam; PF03731; Ku_N; 1.
DR Pfam; PF08785; Ku_PK_bind; 1.
DR PIRSF; PIRSF016570; Ku80; 1.
DR SMART; SM00559; Ku78; 1.
DR SUPFAM; SSF101420; C-terminal domain of Ku80; 1.
DR SUPFAM; SSF100939; SPOC domain-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000052967}.
FT DOMAIN 1..153
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 538..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 679..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..708
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ28286.1"
FT NON_TER 720
FT /evidence="ECO:0000313|EMBL:KFQ28286.1"
SQ SEQUENCE 720 AA; 82189 MW; 737AA659D38308F7 CRC64;
AIVLCLDVGF TMSSSAPGEE SSLEQAKKIM TKFVQRQVFA ESKDEVAVVL FGTDDTRNDL
ACEDQYQNIT IHRSLMLPDF DLMEDIQDVI KAGSEQADFL DAIIVCMDLL QKETIGKKYE
KKHIELFTDL SSPVSEDQLE IIIDNLKKTG ISLQFFLPFP VDVDDGGGDT STSVWSTHRN
SFPRKGLTEQ QKEGINVVRK LMHTLDEEGG LEEVYTFRES LERLSMFKKI ERRPMAWPCQ
LTIGSNLSIR IVAYKSVTEE KVKKIWTVVD AKTHRKDDVQ RETVYCLNDD DETEVQKDDT
IQGFRYGSDI IPFSKEDEEQ MKYKTEAKCF SVLGFTRSSQ IQRHYYMGNQ VLKVFAAKDD
ENAAVAFSAL IHALHELKVV AIVRYAYDRR CNPQVGVAFP HIKDAYECLI YVQLPFTEDL
RQYLFSSLKN NKKCIPTADQ LSAVDSLIDS MNLVYEDDNG ETFEDLFKPS KIPNPQFQRL
YQCLQHKAFH PNEPLPPIEQ HLLEMLEMPC VVKERCQSPL EKVKALFPLK EVGKKKEDKT
AQDIFKDNED GPNPKKPKIE DEEGSFSIVK LAEGSVTSVG SVNPAEDFRI LVRQKNADFR
DVSQQLINRI DQFLENKGSQ YYMKGINCIS VFREEAMKLS RVQCFNDFLQ ALKSKVEDKA
LADFWEIMIQ DRISLISKDE AEESSVTSEE AEKFLAPKEK KNEPLPPTDE GGDVDDLVSI
//
