ID A0A091RIB3_9GRUI Unreviewed; 624 AA.
AC A0A091RIB3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE SubName: Full=Neurofilament heavy polypeptide {ECO:0000313|EMBL:KFQ39007.1};
DE Flags: Fragment;
GN ORFNames=N332_06007 {ECO:0000313|EMBL:KFQ39007.1};
OS Mesitornis unicolor (brown roatelo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis.
OX NCBI_TaxID=54374 {ECO:0000313|EMBL:KFQ39007.1, ECO:0000313|Proteomes:UP000053369};
RN [1] {ECO:0000313|EMBL:KFQ39007.1, ECO:0000313|Proteomes:UP000053369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N332 {ECO:0000313|EMBL:KFQ39007.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; KK818004; KFQ39007.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091RIB3; -.
DR Proteomes; UP000053369; Unassembled WGS sequence.
DR GO; GO:0005883; C:neurofilament; IEA:InterPro.
DR GO; GO:0061564; P:axon development; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR033183; NF-H.
DR PANTHER; PTHR23214:SF1; NEUROFILAMENT HEAVY POLYPEPTIDE; 1.
DR PANTHER; PTHR23214; NEUROFILAMENT TRIPLET H PROTEIN; 1.
DR Pfam; PF00038; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000053369}.
FT DOMAIN 1..120
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 165..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 32..91
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 169..207
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..429
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..528
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..610
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ39007.1"
FT NON_TER 624
FT /evidence="ECO:0000313|EMBL:KFQ39007.1"
SQ SEQUENCE 624 AA; 68106 MW; D1516A932C0CCF7C CRC64;
TVRLDKLSEV AKVNTDAIRL AQEEICEYRR QLQSKTTELE ALKGTQESLE RQRQDSEERH
HADVLSYQET IQQLDSELRN TKWEMAAQLR EYQDLLNVKM ALDIEIAAYR KLLEGEEYRI
ESGFGMISFP EVVPKAPSIA TNIKVKSEEK IKVVEKSEKE TVIVEEQTEE IQVTEEVTEE
DEAEKEAEEE KAEEEEEEEE EKAEAEGEEE EAKSPAKEEA KSPEKPESPS KEEAKSPAVK
SPEKPPTPSK EEAKTPAVKS PEKPATPSKE EAKSPAVKSP EKPATPSKEE AKSPAVKSPE
KPATPLKEEA KSPAVKSPEK PATPLKEEAK SPAVKSPEKP ATPLKEEAKT PAVKSQEKLP
TPSKEEAKTP AVKSPEKPPT PSKEEAKTPA VKSPEKPAPP SKEEAKTPVV KSPEKPAPPS
KEEAKTPAVK SPEKPPTPSK EGAKTPTVKS PEKVKSPVKE AKSPQKEATP TKEPTPSPPK
EPKTPAKEEQ PKETKAASKP GAEEGRKEEA PKKEVPAKVE EKPKEKAAAV PEPPAPQVKE
TTKPAPKPAE EKAEKEAPPK PQQEVGKASA KEAEKPKAEE KVEEPKAKAK PKDEPKASKE
PPKAEAPSSK EGKAPEPAPT TGKK
//
