ID A0A091RUV2_NESNO Unreviewed; 426 AA.
AC A0A091RUV2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|EMBL:KFQ46253.1};
DE Flags: Fragment;
GN ORFNames=N333_06376 {ECO:0000313|EMBL:KFQ46253.1};
OS Nestor notabilis (Kea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Nestor.
OX NCBI_TaxID=176057 {ECO:0000313|EMBL:KFQ46253.1, ECO:0000313|Proteomes:UP000053840};
RN [1] {ECO:0000313|EMBL:KFQ46253.1, ECO:0000313|Proteomes:UP000053840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N333 {ECO:0000313|EMBL:KFQ46253.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK933794; KFQ46253.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091RUV2; -.
DR Proteomes; UP000053840; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF26; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 5; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000053840}.
FT DOMAIN 1..125
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 269..426
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ46253.1"
FT NON_TER 426
FT /evidence="ECO:0000313|EMBL:KFQ46253.1"
SQ SEQUENCE 426 AA; 50018 MW; C44BF44A24CEF42E CRC64;
FLSSSAETLL DDFLLTYTVF MTTDDLCQAL LRQYPFINYL IICSLTCCTY CAKNHQGKED
DSDVSCRKRK VLHLVSQWTS LYKDWLHEDE HLKQFLKTIY RNVLDDVYEY PILEKDLKEF
QKILGMHRRH TVDEYSPHRK NKTFFHQFSL KENWLQHRGT MNETEEIFCR VYITEHSYVS
VKAQVSTSAQ EILKIVAEKI QYPEEELVLV TVTFSGEKHE LQPNDLAISK SLESSSRMFV
YRKDLTDSLH PFAENEELQQ RSVRILGINT WDLALELTNF DWSLFNAIHE QELIYFTFSR
QGSAENTENL SLLLQRCNEV QLWVATEILL CSQLFKRVQL VKKFIKIAAH CKAQRNLNSF
FAIVMGLNTA SVSRLSQTWE KIPGKFKKLF TELESLTDPS LNHKAYRDAF KKMKSPKIPF
MPLLLK
//
