ID A0A091UGR8_PHORB Unreviewed; 383 AA.
AC A0A091UGR8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Substance-P receptor {ECO:0000256|ARBA:ARBA00013755};
DE AltName: Full=NK-1 receptor {ECO:0000256|ARBA:ARBA00031678};
DE AltName: Full=Tachykinin receptor 1 {ECO:0000256|ARBA:ARBA00031714};
DE Flags: Fragment;
GN ORFNames=N337_03374 {ECO:0000313|EMBL:KFQ89661.1};
OS Phoenicopterus ruber ruber.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Phoenicopteriformes; Phoenicopteridae;
OC Phoenicopterus.
OX NCBI_TaxID=9218 {ECO:0000313|EMBL:KFQ89661.1, ECO:0000313|Proteomes:UP000053700};
RN [1] {ECO:0000313|EMBL:KFQ89661.1, ECO:0000313|Proteomes:UP000053700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N337 {ECO:0000313|EMBL:KFQ89661.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK433706; KFQ89661.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091UGR8; -.
DR Proteomes; UP000053700; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004995; F:tachykinin receptor activity; IEA:InterPro.
DR CDD; cd16002; 7tmA_NK1R; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR001681; Neurokn_rcpt.
DR InterPro; IPR000046; NK1_rcpt.
DR PANTHER; PTHR46925; G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED; 1.
DR PANTHER; PTHR46925:SF4; SUBSTANCE-P RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01024; NEUROKININ1R.
DR PRINTS; PR00244; NEUROKININR.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR601681-50};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000053700};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..284
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 359..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 84..159
FT /evidence="ECO:0000256|PIRSR:PIRSR601681-50"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ89661.1"
FT NON_TER 383
FT /evidence="ECO:0000313|EMBL:KFQ89661.1"
SQ SEQUENCE 383 AA; 43917 MW; 2B01149991A1544A CRC64;
ANQFVQPPWQ VALWAVAYAL IVVVSVVGNV VVIWIILAHK RMRTVTNYFL VNLAFAEASM
SAFNTVVNFT YAIHNEWYYG LVYCKFHNFF PIAAVFASIY SMTAIALDRY MAIIHPLQPR
LSATATKVVI GIIWLLAFLL AFPQGYYSVM EELPGRLVCL VEWPEHSSNV YGKTYHFCMT
ILIYFLPLLV IGCAYTVVGI TLWASEIPGD SSDRYHEQVS AKRKVVKMMI IVVCTFALCW
LPYHIYFTLQ HFNPDWYLQK FIQQVYLAIM WLAMSSTMYN PIIYCCLNDR FRVGFKHAFR
WCPFVSAGEY EGLEMKSTRY LQTQTSMYKV SRIETTMSSA VGVAEEELEE SSKAKRLSID
MTSNGSSRSD SKTVSESFSF YSN
//
