ID A0A091VGU8_NIPNI Unreviewed; 442 AA.
AC A0A091VGU8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=tRNA pseudouridine(38/39) synthase {ECO:0000313|EMBL:KFR01970.1};
DE Flags: Fragment;
GN ORFNames=Y956_07377 {ECO:0000313|EMBL:KFR01970.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFR01970.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFR01970.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFR01970.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC {ECO:0000256|ARBA:ARBA00009375}.
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DR EMBL; KL411002; KFR01970.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091VGU8; -.
DR STRING; 128390.A0A091VGU8; -.
DR eggNOG; KOG2554; Eukaryota.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02569; PseudoU_synth_ScPus3; 1.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR HAMAP; MF_00171; TruA; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR001406; PsdUridine_synth_TruA.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR041707; Pus3-like.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR NCBIfam; TIGR00071; hisT_truA; 1.
DR PANTHER; PTHR11142; PSEUDOURIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11142:SF5; TRNA PSEUDOURIDINE(38_39) SYNTHASE; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 216..333
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
FT REGION 28..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 442
FT /evidence="ECO:0000313|EMBL:KFR01970.1"
SQ SEQUENCE 442 AA; 50134 MW; EE5CF2FD5D808311 CRC64;
MAEGSAATDR ERLLRRVQEL EEEVKRLHEK LREDKEGAGR SEAPSASGKA KKRQRRPFDF
GAYGRRHVAL KIAYLGWGYQ GFASQENTSN TIEEKLFEAL KKTRLVDDRQ TSNYHRCGRT
DKGVSAFGQV ISLDLRSSLS EGKKLNGHEG GSEGRSDGEE ELRYTHILNR VLPPDIRVLA
WAPVEPDFSA RFSCLKRTYR YFFPCADLDV ALMHAAAQRY VGSHDFRNLC KMDVANGVVN
FQRTILSAGV TWVERGGETG PQDPFRLCQF EVTGQAFLYH QVRCMMAILF LIGQRMESPE
IIDELLDVEK NPRKPQYSMA VEFPLVLYDC EFENLQWLYD REVQEFNVTH LQQLWANHAV
KTQVLRNMLR GLDAAPVAAG KSPGSGGTVL WGDAKPPLRS QVSGFVEGVK ARTYKPLLAR
PKCEGLEARI RHFVRRGRIE SP
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