ID   A0A091VHC6_NIPNI        Unreviewed;       591 AA.
AC   A0A091VHC6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};
DE   Flags: Fragment;
GN   ORFNames=Y956_09601 {ECO:0000313|EMBL:KFR02484.1};
OS   Nipponia nippon (Crested ibis) (Ibis nippon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC   Nipponia.
OX   NCBI_TaxID=128390 {ECO:0000313|EMBL:KFR02484.1, ECO:0000313|Proteomes:UP000053283};
RN   [1] {ECO:0000313|EMBL:KFR02484.1, ECO:0000313|Proteomes:UP000053283}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFR02484.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Gamma-tubulin complex is necessary for microtubule nucleation
CC       at the centrosome. {ECO:0000256|RuleBase:RU363050}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
CC   -!- SIMILARITY: Belongs to the TUBGCP family.
CC       {ECO:0000256|ARBA:ARBA00010337, ECO:0000256|RuleBase:RU363050}.
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DR   EMBL; KL411013; KFR02484.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091VHC6; -.
DR   STRING; 128390.A0A091VHC6; -.
DR   eggNOG; KOG2065; Eukaryota.
DR   Proteomes; UP000053283; Unassembled WGS sequence.
DR   GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR   GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR   GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR   Gene3D; 1.20.120.1900; Gamma-tubulin complex, C-terminal domain; 1.
DR   InterPro; IPR007259; GCP.
DR   InterPro; IPR040457; GCP_C.
DR   InterPro; IPR042241; GCP_C_sf.
DR   InterPro; IPR041470; GCP_N.
DR   PANTHER; PTHR19302; GAMMA TUBULIN COMPLEX PROTEIN; 1.
DR   PANTHER; PTHR19302:SF27; GAMMA-TUBULIN COMPLEX COMPONENT 4; 1.
DR   Pfam; PF04130; GCP_C_terminal; 1.
DR   Pfam; PF17681; GCP_N_terminal; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU363050};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW   ECO:0000256|RuleBase:RU363050};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU363050};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053283}.
FT   DOMAIN          9..276
FT                   /note="Gamma tubulin complex component protein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17681"
FT   DOMAIN          279..583
FT                   /note="Gamma tubulin complex component C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04130"
FT   REGION          353..372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        353..368
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFR02484.1"
FT   NON_TER         591
FT                   /evidence="ECO:0000313|EMBL:KFR02484.1"
SQ   SEQUENCE   591 AA;  67492 MW;  719BBB19281CFAEB CRC64;
     QDHHPSQQNQ SGLHGIYLRA FCTGLDSVLQ PYRQALLDLE QEFLADPHLS ISHVNYSLDQ
     FQLLFPSVMV MVEQIKTQKI HGCQILETVH KHSCGGLPPV RSALEKILAV CHGVMYKQLS
     AWMLHGLLLD QHEEFFIKQG PSSGNVPSQP EEDDDDLGIG GLTGKQLREL QDLRLIEEEN
     MLAPSLKQFS LRVEMLPSYI PVRVAEKILF VGESVQMFEN QNVNLTRKGS ILKNQEDTFA
     AELHRLKQQP VVDFESVVDW IRSTVAEHLW KLMVEESDLL GQLKIIKDFY LLGRGELFQA
     FIDTAQHMLK TPPTAVTEHD VNVAFQQSAH KVLLDDDNLL PLLHLTIEYH GKEHKDTSQT
     REGPSRELSP REAPASGWAA LGLSYKVQWP LHILFTPAVL EKYNVVFKYL LSVRRVQAEL
     QHCWALQMQR KHLKSNRTDA IKWRLRDHMA FLVDNLQYYL QVDVLESQFS QLLQQINATR
     DFESIRLAHD HFLSNLLAQS FILLKPVFHC LNEILDLCHS FCSLVSQNLG PLDERGAAQL
     SILVKGFSRQ SSLLFKILSS VRNHQINSDL AQLLLRLDYN KYYTQAGGTL G
//