ID A0A091WEY8_OPIHO Unreviewed; 716 AA.
AC A0A091WEY8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|EMBL:KFR14114.1};
DE Flags: Fragment;
GN ORFNames=N306_02972 {ECO:0000313|EMBL:KFR14114.1};
OS Opisthocomus hoazin (Hoatzin) (Phasianus hoazin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Opisthocomiformes; Opisthocomidae;
OC Opisthocomus.
OX NCBI_TaxID=30419 {ECO:0000313|EMBL:KFR14114.1, ECO:0000313|Proteomes:UP000053605};
RN [1] {ECO:0000313|EMBL:KFR14114.1, ECO:0000313|Proteomes:UP000053605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N306 {ECO:0000313|EMBL:KFR14114.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK735436; KFR14114.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091WEY8; -.
DR STRING; 30419.A0A091WEY8; -.
DR PhylomeDB; A0A091WEY8; -.
DR Proteomes; UP000053605; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007420; P:brain development; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR047161; GIT-like.
DR InterPro; IPR032352; GIT1/2_CC.
DR InterPro; IPR022018; GIT1_C.
DR InterPro; IPR013724; GIT_SHD.
DR PANTHER; PTHR46097:SF4; ARF GTPASE-ACTIVATING PROTEIN GIT2; 1.
DR PANTHER; PTHR46097; G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF12205; GIT1_C; 1.
DR Pfam; PF16559; GIT_CC; 1.
DR Pfam; PF08518; GIT_SHD; 2.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00555; GIT; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053605};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 1..110
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REPEAT 152..184
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 364..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 430..464
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 472..491
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..558
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..573
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFR14114.1"
FT NON_TER 716
FT /evidence="ECO:0000313|EMBL:KFR14114.1"
SQ SEQUENCE 716 AA; 80040 MW; 4E08FD502840CEDA CRC64;
SFSDPCWASI NRGILICDEC CSVHRSLGRH ISQVRHLKHT PWPPTLLQMV ETLYNNGANS
IWEHSLLDPA SVMSGRRKAS PQDKVHPNKA EFIRAKYQML AFVHRLPCRE DDSVTAKDLS
KQLHSSVRTG NLETCLRLLS LGAQANFFHP EKGNTPLHVA AKAGQTLQAE LLAVYGADPG
TQDSNGKTPV DCARQGGHHE LAERLVEIQY ELTDRLAFYL CGRKPEHKNG QHFVIPQMAD
SSLDLSELAK AAKKKLQSLS NHLFEELAMD VYDEVDRRET DAVWLATQNH STLVTETTVV
PFLPVNPEYS STRNQGRQKL ARFNAHEFAT LVIDILSDAK RRQQGNSLTG SKENVELILK
SISNQHSSES QDNDQPDYDS VASDEDTDLD INAAKSNRQK SLDSDLSDGP VTPQEYMQVK
NALVASEVKI QQLMKVNINL SDELRIMQKK LQTLQSENTN LRRQATTNIY QVQTGSEYTD
PTNNSSLKRR PSARGSRPMS MYETGSGQKP YLPMGEVPYP EESITRLQPF PPHIGRSAFV
TSSSSLPSFP STLSWSRDES TRRASKLEKQ SSVSESDYDN PTAALELEET GSSLPSTEDV
IRKTEQITKN IQELLRAAQE NKHDSYIPCS ERIHVAVTEM AALFPKKPKS ELVRTSLRLL
TSSAYRLQSE CKKTLPVETC PTTDIQLVTQ QVIQCAYDIA KAAKQLVTIT TKENNN
//
